{"title":"Music therapy for mental health in children and adolescents: a systematic review and meta-analysis of randomized trials.","authors":"Zhiyong Zhang, Ming Ye, Lin Zhang","doi":"10.1186/s13034-026-01102-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Child and adolescent mental disorders impose substantial individual and societal burdens. This study synthesized randomized evidence on the effects of music therapy on depressive and anxiety symptoms, self-esteem, and health-related quality of life in young people, and explored whether intervention characteristics were associated with variations in effect estimates.</p><p><strong>Methods: </strong>Following PRISMA 2020, this review was retrospectively registered with PROSPERO (CRD420261382585). PubMed, Embase, Cochrane CENTRAL, Web of Science, Google Scholar, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform were searched from inception to July 31, 2025, without language limits. Eligible studies were randomized controlled trials enrolling participants aged 6 to 18 years; comparators were no treatment, waitlist, attention control, or usual care; the planned intervention duration was at least four weeks; and outcomes were validated continuous measures at end of treatment. Random-effects models with restricted maximum likelihood generated standardized mean differences (SMD) and 95 percent confidence intervals. Prespecified moderators included age group, session length, session frequency, program duration, and adherence.</p><p><strong>Results: </strong>Nine trials (n = 690) met inclusion criteria. Music therapy reduced depressive symptoms versus controls (SMD - 0.55; 95% CI, - 0.71 to - 0.38) and improved self-esteem (SMD 0.45; 95% CI, 0.26 to 0.64) and quality of life (SMD 0.69; 95% CI, 0.37 to 1.01). Two trials showed reduced anxiety (SMD - 0.42; 95% CI, - 0.75 to - 0.08). Exploratory subgroup analyses suggested larger effect estimates in younger children and in interventions with longer sessions, higher weekly frequency, longer duration, and higher adherence; however, these findings should be interpreted cautiously given the small number of trials.</p><p><strong>Conclusion: </strong>Music therapy may offer meaningful benefits for youth mental health, although evidence for anxiety and quality of life is based on a limited number of studies. Findings related to age and intervention delivery characteristics should be considered exploratory and hypothesis-generating rather than evidence of causality or optimal dosing.</p>","PeriodicalId":9934,"journal":{"name":"Child and Adolescent Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13584578/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Child and Adolescent Psychiatry and Mental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13034-026-01102-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Child and adolescent mental disorders impose substantial individual and societal burdens. This study synthesized randomized evidence on the effects of music therapy on depressive and anxiety symptoms, self-esteem, and health-related quality of life in young people, and explored whether intervention characteristics were associated with variations in effect estimates.
Methods: Following PRISMA 2020, this review was retrospectively registered with PROSPERO (CRD420261382585). PubMed, Embase, Cochrane CENTRAL, Web of Science, Google Scholar, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform were searched from inception to July 31, 2025, without language limits. Eligible studies were randomized controlled trials enrolling participants aged 6 to 18 years; comparators were no treatment, waitlist, attention control, or usual care; the planned intervention duration was at least four weeks; and outcomes were validated continuous measures at end of treatment. Random-effects models with restricted maximum likelihood generated standardized mean differences (SMD) and 95 percent confidence intervals. Prespecified moderators included age group, session length, session frequency, program duration, and adherence.
Results: Nine trials (n = 690) met inclusion criteria. Music therapy reduced depressive symptoms versus controls (SMD - 0.55; 95% CI, - 0.71 to - 0.38) and improved self-esteem (SMD 0.45; 95% CI, 0.26 to 0.64) and quality of life (SMD 0.69; 95% CI, 0.37 to 1.01). Two trials showed reduced anxiety (SMD - 0.42; 95% CI, - 0.75 to - 0.08). Exploratory subgroup analyses suggested larger effect estimates in younger children and in interventions with longer sessions, higher weekly frequency, longer duration, and higher adherence; however, these findings should be interpreted cautiously given the small number of trials.
Conclusion: Music therapy may offer meaningful benefits for youth mental health, although evidence for anxiety and quality of life is based on a limited number of studies. Findings related to age and intervention delivery characteristics should be considered exploratory and hypothesis-generating rather than evidence of causality or optimal dosing.
期刊介绍:
Child and Adolescent Psychiatry and Mental Health, the official journal of the International Association for Child and Adolescent Psychiatry and Allied Professions, is an open access, online journal that provides an international platform for rapid and comprehensive scientific communication on child and adolescent mental health across different cultural backgrounds. CAPMH serves as a scientifically rigorous and broadly open forum for both interdisciplinary and cross-cultural exchange of research information, involving psychiatrists, paediatricians, psychologists, neuroscientists, and allied disciplines. The journal focusses on improving the knowledge base for the diagnosis, prognosis and treatment of mental health conditions in children and adolescents, and aims to integrate basic science, clinical research and the practical implementation of research findings. In addition, aspects which are still underrepresented in the traditional journals such as neurobiology and neuropsychology of psychiatric disorders in childhood and adolescence are considered.