Fertility preservation by ex vivo oocyte retrieval in a 17-year-old with bilateral borderline ovarian tumors: a case report.

IF 1.9

JBRA assisted reproduction Pub Date : 2026-04-01 DOI:10.5935/1518-0557.20260011

Rodrigo Guimarães Furtado, Francisco Furtado, Reitan Ribeiro, Ivana Rippel Hauer, Luiza Sonaglio, Fabricio Furtado, Gustavo Wandresen, Renato Nisihara

{"title":"Fertility preservation by ex vivo oocyte retrieval in a 17-year-old with bilateral borderline ovarian tumors: a case report.","authors":"Rodrigo Guimarães Furtado, Francisco Furtado, Reitan Ribeiro, Ivana Rippel Hauer, Luiza Sonaglio, Fabricio Furtado, Gustavo Wandresen, Renato Nisihara","doi":"10.5935/1518-0557.20260011","DOIUrl":null,"url":null,"abstract":"<p><p>We report a case of fertility preservation through ex vivo oocyte aspiration in an adolescent who underwent bilateral oophorectomy due to asynchronous borderline ovarian tumors. A 17-year-old nulligravid patient was initially diagnosed with a left-sided serous borderline ovarian tumor and treated with left salpingo-oophorectomy. One year later, a lesion was identified in the contralateral ovary, with surgical indication for salpingo-oophorectomy. Ovarian stimulation was performed using recombinant FSH and hMG, with final oocyte maturation triggered by a GnRH agonist. Oocyte retrieval was conducted ex vivo, immediately after surgical removal of the ovary. A total of 13 oocytes were obtained, 10 of which were in metaphase II and successfully cryopreserved. This case highlights the feasibility and efficacy of ex vivo oocyte retrieval as a fertility preservation strategy in oncology patients requiring urgent bilateral oophorectomy.</p>","PeriodicalId":520656,"journal":{"name":"JBRA assisted reproduction","volume":"30 2","pages":"424-429"},"PeriodicalIF":1.9000,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13318286/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JBRA assisted reproduction","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5935/1518-0557.20260011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

We report a case of fertility preservation through ex vivo oocyte aspiration in an adolescent who underwent bilateral oophorectomy due to asynchronous borderline ovarian tumors. A 17-year-old nulligravid patient was initially diagnosed with a left-sided serous borderline ovarian tumor and treated with left salpingo-oophorectomy. One year later, a lesion was identified in the contralateral ovary, with surgical indication for salpingo-oophorectomy. Ovarian stimulation was performed using recombinant FSH and hMG, with final oocyte maturation triggered by a GnRH agonist. Oocyte retrieval was conducted ex vivo, immediately after surgical removal of the ovary. A total of 13 oocytes were obtained, 10 of which were in metaphase II and successfully cryopreserved. This case highlights the feasibility and efficacy of ex vivo oocyte retrieval as a fertility preservation strategy in oncology patients requiring urgent bilateral oophorectomy.

查看原文本刊更多论文

17岁双侧交界性卵巢肿瘤患者体外取卵保存生育能力1例。

我们报告一例通过体外卵母细胞抽吸保存生育能力的青少年谁接受了双侧卵巢切除术，由于异步交界性卵巢肿瘤。一名17岁的无输卵管患者最初被诊断为左侧浆液性交界性卵巢肿瘤，并接受左侧输卵管卵巢切除术治疗。一年后，在对侧卵巢发现病变，手术指征为输卵管卵巢切除术。使用重组FSH和hMG进行卵巢刺激，最终由GnRH激动剂触发卵母细胞成熟。在手术切除卵巢后立即进行体外卵母细胞提取。共获得13个卵母细胞，其中10个卵母细胞处于中期，并成功冷冻保存。本病例强调了体外卵母细胞回收作为需要紧急双侧卵巢切除术的肿瘤患者生育能力保存策略的可行性和有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

JBRA assisted reproduction

自引率

0.00%

发文量