{"title":"Adverse childhood experiences and well-being in middle-aged men in South Korea: mediating role of andropause symptoms.","authors":"Jeongok Park, Youngkyung Kim, Hyunju Lee","doi":"10.1186/s12955-026-02569-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Middle-aged men in South Korea are in a critical period marked by significant physical and psychosocial transitions. While adverse childhood experiences negatively affect lifelong health, the specific mechanisms affecting well-being during midlife remain underexplored. This study aimed to examine the mediating role of andropause symptoms in the relationship between adverse childhood experiences (ACEs) and well-being.</p><p><strong>Methods: </strong>A cross-sectional survey involving 444 community-dwelling Korean men aged 40-64 years was conducted from June to August 2024. Data were collected via an online questionnaire to assess ACEs, andropause symptoms, and well-being. The SAS 9.4 and PROCESS macro were used for data analysis.</p><p><strong>Results: </strong>The participants had a mean age of 50.8 years. High levels of well-being were significantly associated with being married, higher educational attainment, and higher income. Participants reporting high ACEs had significantly lower levels of well-being than those reporting no ACEs. In the mediating analysis, the indirect effect of andropause symptoms on the relationships between ACEs and well-being was statistically significant (β = -0.08, 95% CI = -0.109 to -0.053). This finding suggests that andropause symptoms partially mediate the relationship between ACEs and well-being in middle-aged men.</p><p><strong>Conclusions: </strong>Andropause symptoms appeared to partially mediated the relationship between ACEs and well-being in middle-aged Korean men. Although both ACEs and andropause symptoms are associated with midlife well-being, they have rarely been addressed together. Community-based programs combining trauma-informed counseling and andropause management are needed to improve well-being in middle-aged men.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548565/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Health and Quality of Life Outcomes","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12955-026-02569-x","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Middle-aged men in South Korea are in a critical period marked by significant physical and psychosocial transitions. While adverse childhood experiences negatively affect lifelong health, the specific mechanisms affecting well-being during midlife remain underexplored. This study aimed to examine the mediating role of andropause symptoms in the relationship between adverse childhood experiences (ACEs) and well-being.
Methods: A cross-sectional survey involving 444 community-dwelling Korean men aged 40-64 years was conducted from June to August 2024. Data were collected via an online questionnaire to assess ACEs, andropause symptoms, and well-being. The SAS 9.4 and PROCESS macro were used for data analysis.
Results: The participants had a mean age of 50.8 years. High levels of well-being were significantly associated with being married, higher educational attainment, and higher income. Participants reporting high ACEs had significantly lower levels of well-being than those reporting no ACEs. In the mediating analysis, the indirect effect of andropause symptoms on the relationships between ACEs and well-being was statistically significant (β = -0.08, 95% CI = -0.109 to -0.053). This finding suggests that andropause symptoms partially mediate the relationship between ACEs and well-being in middle-aged men.
Conclusions: Andropause symptoms appeared to partially mediated the relationship between ACEs and well-being in middle-aged Korean men. Although both ACEs and andropause symptoms are associated with midlife well-being, they have rarely been addressed together. Community-based programs combining trauma-informed counseling and andropause management are needed to improve well-being in middle-aged men.
期刊介绍:
Health and Quality of Life Outcomes is an open access, peer-reviewed, journal offering high quality articles, rapid publication and wide diffusion in the public domain.
Health and Quality of Life Outcomes considers original manuscripts on the Health-Related Quality of Life (HRQOL) assessment for evaluation of medical and psychosocial interventions. It also considers approaches and studies on psychometric properties of HRQOL and patient reported outcome measures, including cultural validation of instruments if they provide information about the impact of interventions. The journal publishes study protocols and reviews summarising the present state of knowledge concerning a particular aspect of HRQOL and patient reported outcome measures. Reviews should generally follow systematic review methodology. Comments on articles and letters to the editor are welcome.