Sleep and exercise can limit clonal haematopoiesis clone expansion and reduce associated atherosclerosis

IF 50.2 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Nature Reviews Cardiology Pub Date : 2026-06-22 DOI:10.1038/s41569-026-01318-3

Karina Huynh

引用次数: 0

Abstract

A study in Nature reports that in mice, healthy lifestyle behaviours, including exercise and uninterrupted sleep, can limit clone expansion in clonal haematopoiesis and promote the phenotypic reprogramming of clonal haematopoiesis mutant cells, thereby reducing the risk of atherosclerosis.

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睡眠和运动可以限制克隆造血克隆扩张，减少相关的动脉粥样硬化。

《自然》杂志的一项研究报道，在小鼠中，健康的生活方式行为，包括运动和不间断的睡眠，可以限制克隆造血中的克隆扩增，促进克隆造血突变细胞的表型重编程，从而降低动脉粥样硬化的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Cardiology 医学-心血管系统

CiteScore

53.10

自引率

0.60%

发文量

143

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cardiology aims to be the go-to source for reviews and commentaries in the scientific and clinical communities it serves. Focused on providing authoritative and accessible articles enriched with clear figures and tables, the journal strives to offer unparalleled service to authors, referees, and readers, maximizing the usefulness and impact of each publication. It covers a broad range of content types, including Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives, catering to practising cardiologists and cardiovascular research scientists. Authored by renowned clinicians, academics, and researchers, the content targets readers in the biological and medical sciences, ensuring accessibility across various disciplines. In-depth Reviews offer up-to-date information, while Consensus Statements provide evidence-based recommendations. Perspectives and News & Views present topical discussions and opinions, and the Research Highlights section filters primary research from cardiovascular and general medical journals. As part of the Nature Reviews portfolio, Nature Reviews Cardiology maintains high standards and a wide reach.