{"title":"Potential role of natural products in veterinary stem cell therapy.","authors":"Asiyeh Shojaee","doi":"10.1186/s13287-026-05117-y","DOIUrl":null,"url":null,"abstract":"<p><p>In veterinary medicine, stem cells therapy is mostly used to treatment of orthopedic condition. Stem cell behavior is shaped by numerous intrinsic and extrinsic factors. Traditional medicinal herbs-long used to prevent and treat diverse diseases-together with other natural bioactive compounds have attracted increasing interest because of their potential to modulate stem cell function. Many of these agents exhibit antioxidant, anti-inflammatory, anticancer, and anti-apoptotic activities and may support tissue regeneration by enhancing proliferation, differentiation, and migration. Importantly, natural products may offer safer and more cost-effective alternatives to synthetic growth factors in regenerative strategies. Accordingly, this review summarizes recent evidence on medicinal plants, phytochemicals, algal extracts, and related bioactive compounds that influence veterinary stem cells, and discusses their potential applications in regenerative medicine.</p>","PeriodicalId":21876,"journal":{"name":"Stem Cell Research & Therapy","volume":" ","pages":""},"PeriodicalIF":7.8000,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479437/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem Cell Research & Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13287-026-05117-y","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0
Abstract
In veterinary medicine, stem cells therapy is mostly used to treatment of orthopedic condition. Stem cell behavior is shaped by numerous intrinsic and extrinsic factors. Traditional medicinal herbs-long used to prevent and treat diverse diseases-together with other natural bioactive compounds have attracted increasing interest because of their potential to modulate stem cell function. Many of these agents exhibit antioxidant, anti-inflammatory, anticancer, and anti-apoptotic activities and may support tissue regeneration by enhancing proliferation, differentiation, and migration. Importantly, natural products may offer safer and more cost-effective alternatives to synthetic growth factors in regenerative strategies. Accordingly, this review summarizes recent evidence on medicinal plants, phytochemicals, algal extracts, and related bioactive compounds that influence veterinary stem cells, and discusses their potential applications in regenerative medicine.
期刊介绍：
Stem Cell Research & Therapy serves as a leading platform for translational research in stem cell therapies. This international, peer-reviewed journal publishes high-quality open-access research articles, with a focus on basic, translational, and clinical research in stem cell therapeutics and regenerative therapies. Coverage includes animal models and clinical trials. Additionally, the journal offers reviews, viewpoints, commentaries, and reports.
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