Prehabilitation Prior to Colorectal Cancer Surgery: Impact and Implementation

IF 1.9 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2026-09-01 Epub Date: 2026-06-18 DOI:10.1002/jso.70305

Elize W. Lockhorst, Theresia A. M. Backhuijs, Teun M. E. Kerkhoff, Robert R. J. Coebergh van den Braak, Ninos Ayez, Cornelis Verhoef, Paul D. Gobardhan, Jennifer M. J. Schreinemakers

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Abstract

Background and Objectives

Multimodal prehabilitation aims to improve surgical outcomes and preoperative fitness in patients undergoing surgery for colorectal cancer (CRC). This study evaluated implementation of a standardised prehabilitation programme for elective CRC surgery, assess its impact, and identify pitfalls and challenges during implementation.

Methods

Retrospective single-centre study, all CRC patients scheduled for resection between January 2022 and April 2024 were included. Since May 2023, standardised multimodal prehabilitation was introduced. Before, patients received physiotherapy and a dietician if indicated, although this was not routinely offered. Patients were divided into a prehabilitation and non-prehabilitation group. Clinical data, prehabilitation details, and physiotherapy results were collected from patient charts.

Results

Among 401 patients, 198 (49%) underwent prehabilitation. Participation increased after standardisation (40% vs. 59%, p < 0.001). Strength and physical fitness improved significantly (leg press 100 vs. 135 kg; steep ramp 160 vs. 213 W; p < 0.001). Patients in the non-standardised programme experienced a significantly longer postoperative hospital stay than those in standardised programme (4 vs. 3 days, p = 0.010). Despite more comorbidities in prehabilitated patients, complication rates were similar between patients without and with prehabilitation (28% vs. 24%, p = 0.45).

Conclusion

Standardised prehabilitation appears beneficial and safe, improving participation, referral justification and outcomes, particularly in high-risk colorectal cancer patients.

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结直肠癌手术前的康复：影响和实施。

背景和目的：多模式康复旨在改善结直肠癌（CRC）手术患者的手术效果和术前健康。本研究评估了选择性结直肠癌手术的标准化康复方案的实施，评估其影响，并确定实施过程中的陷阱和挑战。方法：回顾性单中心研究，纳入2022年1月至2024年4月期间计划切除的所有结直肠癌患者。自2023年5月起，引入标准化多式联运预安置。在此之前，患者接受物理治疗，如果有必要，还会接受营养师的治疗，尽管这并不是常规治疗。患者分为预康复组和非预康复组。临床资料、康复细节和物理治疗结果从患者图表中收集。结果：401例患者中，198例（49%）接受了康复治疗。结论：标准化的康复治疗似乎是有益和安全的，可以改善患者的参与、转诊理由和转归，特别是在高危结直肠癌患者中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.