Performance of Survival Prediction Tools in Patients With Gastrointestinal Stromal Tumors: A Systematic Review and Meta-Analysis

IF 1.9 3区医学 Q3 ONCOLOGY

Journal of Surgical Oncology Pub Date : 2026-09-01 Epub Date: 2026-06-18 DOI:10.1002/jso.70303

Alice Zhu, Chloe Wong, Neill K. J. Adhikari, Ka Yan Ip, Alyson Mahar, Amy T. Hsu, Julie Hallet, Natalie Coburn

引用次数: 0

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We conducted a systematic review and meta-analysis of studies that developed, validated, or updated clinical prognostic tools to predict survival in adults with primary GIST, identifying 47 eligible studies (38 development and 9 validation studies). Meta-analyses were performed to assess performance in external validation cohorts. The MSKCC nomogram was most frequently validated, with a pooled C-statistic of 0.78 for recurrence-free survival.

查看原文本刊更多论文

胃肠道间质瘤患者生存预测工具的性能：系统回顾和荟萃分析。

胃肠道间质瘤（gist）是最常见的胃肠道间质肿瘤。我们对开发、验证或更新的临床预后工具预测成人原发性GIST患者生存的研究进行了系统回顾和荟萃分析，确定了47项符合条件的研究（38项开发研究和9项验证研究）。进行meta分析以评估外部验证队列的表现。MSKCC nomogram最常被验证，无复发生存的总c统计量为0.78。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Surgical Oncology 医学-外科

CiteScore

4.70

自引率

4.00%

发文量

367

审稿时长

2 months

期刊介绍： The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.