ADHD Diagnosis Patterns: Comorbidities and the Impact of Relative Age on Diagnosis Likelihood.

IF 3.2 3区 医学 Q2 PSYCHIATRY
Elisa Westman, Tuire Prami, Alvar Kallio, Ilona Iso-Mustajärvi, Essi J Peltonen, Joel Jukka, Paavo Raittinen, Maarit J Korhonen, Anita Puustjärvi, Sami Leppämäki
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Abstract

Background: Attention deficit hyperactivity disorder (ADHD) has been associated with comorbid conditions, especially psychiatric comorbidities. On the other hand, getting an ADHD diagnosis has been linked to children's relative age. The aim of this study was to describe diagnostic patterns of ADHD patients of all ages, and to compare comorbidity and birth month between ADHD patients and matched controls.

Methods: This nationwide study cohort included incident ADHD patients with records of ADHD medication and/or ADHD diagnosis in Finland during 2015 to 2020, and with no such records during 2010 to 2014. Four controls were matched with each patient based on age, gender, and place of residence.

Results: Altogether 66,146 incident ADHD patients and 256,270 matched controls were identified, and their average follow-up time was 3.5 years. Mean age at the first ADHD diagnosis was 15.9 years for males and 22.3 for females. Prior to being diagnosed with ADHD, patients visited health care remarkably more often than controls. Comorbid diagnoses were the most prevalent at index date, and compared to controls, the prevalence of these comorbidities within 3 years preceding the index date increased more in ADHD patients. The odds of ADHD increased with later birth months across all age-gender groups, except among girls under 6 years of age. The association was more pronounced among males.

Conclusion: ADHD is associated with a significant comorbidity burden across all age groups, even before ADHD diagnosis. Individuals who are younger in relative age are more likely to be diagnosed with ADHD.

ADHD诊断模式:合并症和相对年龄对诊断可能性的影响。
背景:注意缺陷多动障碍(ADHD)与合并症有关,尤其是精神合并症。另一方面,ADHD的诊断与儿童的相对年龄有关。本研究的目的是描述所有年龄段的ADHD患者的诊断模式,并比较ADHD患者和匹配对照组之间的合并症和出生月份。方法:这项全国性的研究队列纳入了芬兰2015年至2020年期间有ADHD药物治疗和/或ADHD诊断记录的ADHD患者,以及2010年至2014年期间没有此类记录的ADHD患者。根据年龄、性别和居住地与每位患者匹配4个对照组。结果:共确定66146例ADHD患者和256270例匹配对照,平均随访时间为3.5年。男性首次诊断ADHD的平均年龄为15.9岁,女性为22.3岁。在被诊断患有注意力缺陷多动障碍之前,患者比对照组更经常地去看医疗保健。合并症诊断在索引日期最普遍,与对照组相比,ADHD患者在索引日期前3年内这些合并症的患病率增加更多。除了6岁以下的女孩外,所有年龄-性别群体中,多动症的几率随着出生月份的增加而增加。这种关联在男性中更为明显。结论:在所有年龄组中,甚至在ADHD诊断之前,ADHD都与显著的共病负担相关。相对年龄较小的个体更有可能被诊断为多动症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.60
自引率
6.70%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.
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