Pedagogy and Enriched Environment for Rehabilitation in the HOME After Stroke (PEER-HOMEcare): Study Protocol for a Single-Group Feasibility Study.

IF 4.2 2区 医学 Q1 CLINICAL NEUROLOGY
Arve Opheim, Luca Oppici, Ann Marie Hestetun-Mandrup, Katharina S Sunnerhagen, Lena Rafsten, Guna Bērziņa, Agnese Kārkliņa, Marianne Løvstad, Hege Prag Øra, Lauren Marcos, Matheus Pacheco, Aléxia Fernandes, Linda Sørensen, James Robert Rudd
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Abstract

Home-based rehabilitation after stroke is increasingly important, as pressure on hospital services rise and recovery occurs mostly at home. Enriching the home (Environmental Enrichment, EE) represents a potential strategy to support rehabilitation by providing continuous task- and context-specific stimulation that promotes functional recovery through frequent and exploratory use of the affected arm. Exploratory behaviour - self-initiated, varied and adaptive movements - is an important driver of motor learning and neuroplasticity. While strong evidence from animal research demonstrates the benefits of EE for functional recovery, translation to human home-based rehabilitation remains limited. This study will investigate the feasibility of the Pedagogy and Enriched Environment for Rehabilitation in the HOME after stroke (PEER-HOMEcare) intervention. PEER-HOMEcare translates EE by introducing meaningful, targeted and progressive home modifications to promote exploratory use of the affected arm during daily activities. In this prospective, single group, experimental study, 45 stroke survivors (≥ 18 years), within 6 months post-stroke across Norway, Sweden and Latvia will participate. Wearable sensors will be used to capture exploratory behaviour and activity patterns, giving objective insights to inform progressive modifications to the home. Primary outcomes of feasibility and acceptability will be assessed through questionnaires, logs and interviews. Intervention fidelity, participant adherence and adverse events will be evaluated. Secondary outcomes include changes in arm function, self-perceived activities of daily living and psychosocial outcomes. This study will provide important knowledge about the feasibility of an innovative EE approach for home-based rehabilitation, informing a future trial evaluating its clinical effectiveness. Trial registration in https://www.ClinicalTrials.gov on 06-04-2026, NCT07517120.

脑卒中后家庭康复的教学方法和丰富的环境(同侪家庭护理):一项单组可行性研究的研究方案。
中风后以家庭为基础的康复越来越重要,因为医院服务压力增加,康复主要在家中进行。丰富家庭环境(Environmental Enrichment, EE)是一种潜在的支持康复的策略,通过提供持续的任务和情境特定的刺激,通过频繁和探索性地使用受影响的手臂来促进功能恢复。探索性行为——自我发起的、多样的和适应性的运动——是运动学习和神经可塑性的重要驱动力。虽然来自动物研究的有力证据表明情感表达对功能恢复的益处,但将其转化为人类家庭康复仍然有限。本研究旨在探讨卒中后家庭康复的教学方法和丰富的环境(PEER-HOMEcare)干预的可行性。PEER-HOMEcare通过引入有意义的、有针对性的、渐进的家庭改造来促进受影响手臂在日常活动中的探索性使用,从而转化情感表达。在这项前瞻性、单组、实验性研究中,来自挪威、瑞典和拉脱维亚的45名中风幸存者(≥18岁)将在中风后6个月内参与研究。可穿戴传感器将用于捕捉探索性行为和活动模式,为逐步改进家庭提供客观见解。可行性和可接受性的主要结果将通过问卷调查、日志和访谈进行评估。评估干预保真度、参与者依从性和不良事件。次要结局包括手臂功能、日常生活自我感知活动和心理社会结局的改变。本研究将为创新的情感表达方法在家庭康复中的可行性提供重要的知识,为未来评估其临床效果的试验提供信息。试验报名:06-04-2026 https://www.ClinicalTrials.gov, NCT07517120。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Translational Stroke Research
Translational Stroke Research CLINICAL NEUROLOGY-NEUROSCIENCES
CiteScore
13.80
自引率
4.30%
发文量
130
审稿时长
6-12 weeks
期刊介绍: Translational Stroke Research covers basic, translational, and clinical studies. The Journal emphasizes novel approaches to help both to understand clinical phenomenon through basic science tools, and to translate basic science discoveries into the development of new strategies for the prevention, assessment, treatment, and enhancement of central nervous system repair after stroke and other forms of neurotrauma. Translational Stroke Research focuses on translational research and is relevant to both basic scientists and physicians, including but not restricted to neuroscientists, vascular biologists, neurologists, neuroimagers, and neurosurgeons.
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