A Systematic Review with Meta-analysis of the Association between Changes in Muscle Strength and Clinical Outcome Changes in Patellofemoral Pain.

IF 11 1区医学 Q1 SPORT SCIENCES

Sports Medicine Pub Date : 2026-11-01 Epub Date: 2026-06-16 DOI:10.1007/s40279-026-02473-w

Guilherme S Nunes, Matheus Weide Solner, Jênifer de Oliveira, Bruna Wageck, Anna Julia Meireles Dangui

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引用次数: 0

Abstract

Objective: To investigate whether muscle strength changes observed in randomised controlled trials involving people with patellofemoral pain (PFP) are associated with concurrent changes in pain and physical function.

Design: Systematic review with meta-analysis, applying a two-stage structural equation modelling approach with random-effects estimation.

Eligibility criteria: Randomised clinical trials assessing non-surgical and non-pharmacological interventions that reported both muscle strength and at least one clinical outcome (pain or function) in people with PFP.

Data sources: CINAHL, Cochrane Library, Embase, Medline and SPORTDiscus were searched from inception to April 2026.

Results: From 16,750 records screened, 82 trials met the eligibility criteria (4023 participants). Regarding self-reported pain outcomes, low to moderate evidence certainty indicated significant associations between strength improvements and pain reduction for knee extensors (r = - 0.75, β = - 0.21), knee flexors (r = - 0.46, β = - 0.14), hip abductors (r = - 0.91, β = - 0.31), hip adductors (r = - 0.26, β = - 0.19), hip external rotators (r = - 0.24, β = - 0.06), hip internal rotators (r = - 0.79, β = - 0.31) and hip extensors (r = - 0.58, β = - 0.26). Regarding self-reported function, low to high evidence certainty indicated that strength improvements in knee extensors (r = 0.70, β = 0.15), knee flexors (r = 0.46, β = 0.07), hip abductors (r = 0.94, β = 0.15), hip adductors (r = 0.55, β = 0.11), and hip internal rotators (r = 0.98, β = 0.06) were significantly associated with improved function.

Conclusions: This review provides evidence that improvements in lower limb muscle strength are associated with improvements in pain and physical function among people with PFP. These findings reinforce the clinical relevance of strength-focused rehabilitation, particularly targeting the knee and hip muscles.

Registration number: CRD42023420875.

查看原文本刊更多论文

髌股疼痛患者肌肉力量变化与临床结果变化相关性的meta分析系统综述。

目的：探讨在髌股疼痛（PFP）患者的随机对照试验中观察到的肌肉力量变化是否与疼痛和身体功能的同步变化有关。设计：采用meta分析的系统综述，采用随机效应估计的两阶段结构方程建模方法。入选标准：评估非手术和非药物干预措施的随机临床试验，这些干预措施报告了PFP患者的肌肉力量和至少一项临床结果（疼痛或功能）。数据来源：检索自成立至2026年4月的CINAHL、Cochrane Library、Embase、Medline和SPORTDiscus。结果：从筛选的16,750条记录中，82项试验符合资格标准（4023名受试者）。关于自我痛苦的结果,低到中等程度的确定性证据表明之间的关联强度明显改善,减少膝盖的疼痛两种(r = - 0.75,β= - 0.21),膝盖屈肌(r = - 0.46,β= - 0.14),臀部绑架者(r = - 0.91,β= - 0.31),髋关节合并(r = - 0.26,β= - 0.19),臀部强大(r = - 0.24,β= - 0.06),髋关节内部强大(r = - 0.79,β= - 0.31)和臀部两种(r = - 0.58,β= - 0.26)。关于自我报告的功能，低至高证据确定性表明，膝关节伸肌（r = 0.70, β = 0.15）、膝关节屈肌（r = 0.46, β = 0.07）、髋关节外展肌（r = 0.94, β = 0.15）、髋关节内收肌（r = 0.55, β = 0.11）和髋关节内旋肌（r = 0.98, β = 0.06）的力量改善与功能改善显著相关。结论：本综述提供的证据表明，下肢肌肉力量的改善与PFP患者疼痛和身体功能的改善有关。这些发现加强了以力量为中心的康复的临床意义，特别是针对膝盖和臀部肌肉。注册号：CRD42023420875。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sports Medicine 医学-运动科学

CiteScore

18.40

自引率

5.10%

发文量

165

审稿时长

6-12 weeks

期刊介绍： Sports Medicine focuses on providing definitive and comprehensive review articles that interpret and evaluate current literature, aiming to offer insights into research findings in the sports medicine and exercise field. The journal covers major topics such as sports medicine and sports science, medical syndromes associated with sport and exercise, clinical medicine's role in injury prevention and treatment, exercise for rehabilitation and health, and the application of physiological and biomechanical principles to specific sports. Types of Articles: Review Articles: Definitive and comprehensive reviews that interpret and evaluate current literature to provide rationale for and application of research findings. Leading/Current Opinion Articles: Overviews of contentious or emerging issues in the field. Original Research Articles: High-quality research articles. Enhanced Features: Additional features like slide sets, videos, and animations aimed at increasing the visibility, readership, and educational value of the journal's content. Plain Language Summaries: Summaries accompanying articles to assist readers in understanding important medical advances. Peer Review Process: All manuscripts undergo peer review by international experts to ensure quality and rigor. The journal also welcomes Letters to the Editor, which will be considered for publication.