Post-pandemic impact on the epidemiology of invasive pneumococcal disease: consensus statement from the Latin American Society of Pediatric Infectious Diseases (SLIPE).

IF 5.6 3区 医学 Q1 IMMUNOLOGY
Expert Review of Vaccines Pub Date : 2026-12-01 Epub Date: 2026-06-19 DOI:10.1080/14760584.2026.2689604
Roberto Debbag, María L Avila-Agüero, Angela Gentile, Jaime Torres, Carlos Torres, Liliana Vazquez, Claudia Beltran, José Brea-Del Castillo, Ron Dagan
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引用次数: 0

Abstract

Introduction: The Latin American Society of Pediatric Infectious Diseases (SLIPE) convened a multidisciplinary expert panel to assess the post-pandemic epidemiology of invasive pneumococcal disease (IPD) in Latin America and the Caribbean. The COVID-19 pandemic initially reduced IPD incidence due to non-pharmaceutical interventions, but subsequent relaxation of restrictions, coupled with immunization gaps, led to a resurgence of pneumococcal infections. The consensus statement reviews literature and regional surveillance data to analyze how disrupted vaccination programs, socioeconomic inequities, and weakened healthcare systems amplified the regional vulnerability to vaccine-preventable diseases.

Areas covered: This document addresses epidemiologic changes in IPD following the pandemic, the interplay between respiratory viral infections and pneumococcal disease, trends in pneumococcal conjugate vaccine (PCV) coverage and related barriers, and the emergence of non-vaccine serotypes causing IPD.

Expert opinion: Sustaining herd protection in the region requires strengthening vaccination infrastructure, restoring confidence through effective communication, and ensuring the completion of booster doses in the second year of life. Despite limited serotype data, countries should prioritize the timely adoption of higher-valency PCVs in feasible schedules to mitigate the growing burden of pneumococcal disease and prevent further setbacks in child health.

大流行后对侵袭性肺炎球菌疾病流行病学的影响:拉丁美洲儿科传染病学会(SLIPE)的共识声明。
拉丁美洲儿科传染病学会(SLIPE)召集了一个多学科专家小组,以评估拉丁美洲和加勒比地区侵袭性肺炎球菌病(IPD)大流行后的流行病学。由于采取了非药物干预措施,COVID-19大流行最初降低了IPD发病率,但随后放宽了限制,再加上免疫缺口,导致肺炎球菌感染死灰复生。共识声明回顾了文献和区域监测数据,以分析疫苗接种计划中断、社会经济不平等和卫生保健系统削弱如何加剧了区域对疫苗可预防疾病的脆弱性。涵盖领域:本文件涉及大流行后IPD的流行病学变化,呼吸道病毒感染与肺炎球菌疾病之间的相互作用,肺炎球菌结合疫苗(PCV)覆盖率的趋势和相关障碍,以及引起IPD的非疫苗血清型的出现。专家意见:在该地区维持群体保护需要加强疫苗接种基础设施,通过有效沟通恢复信心,并确保在生命的第二年完成加强剂量。尽管血清型数据有限,但各国应在可行的时间表内优先考虑及时采用高价pcv,以减轻肺炎球菌疾病日益增加的负担,并防止儿童健康进一步受挫。
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来源期刊
Expert Review of Vaccines
Expert Review of Vaccines 医学-免疫学
CiteScore
9.10
自引率
3.20%
发文量
136
审稿时长
4-8 weeks
期刊介绍: Expert Review of Vaccines (ISSN 1476-0584) provides expert commentary on the development, application, and clinical effectiveness of new vaccines. Coverage includes vaccine technology, vaccine adjuvants, prophylactic vaccines, therapeutic vaccines, AIDS vaccines and vaccines for defence against bioterrorism. All articles are subject to rigorous peer-review. The vaccine field has been transformed by recent technological advances, but there remain many challenges in the delivery of cost-effective, safe vaccines. Expert Review of Vaccines facilitates decision making to drive forward this exciting field.
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