Burn Epidemiology and Outcome Disparities: A Study of Patients Hospitalized With Burns in Pakistan.

IF 1.5 4区 医学 Q3 DERMATOLOGY
Samman Khalid, Sanjana Butala, Zaryab Alam, Ayesha Nazuk, Noah Musolff, Madeline Tchack, Samavia Khan, Husnain Khan, Babar Rao
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引用次数: 0

Abstract

Objective: To investigate demographic, clinical, and outcome disparities among patients hospitalized with burns in Pakistan, with a focus on gender, age, and burn characteristics associated with mortality.

Methods: This retrospective study analyzed data from 389 patients with burns admitted to Holy Family Hospital, Rawalpindi, Pakistan, in 2022. Variables included age, gender, burn etiology, total body surface area (TBSA) burned, comorbidities, and clinical outcomes. Statistical analyses identified associations between these factors and patient outcomes. Binary logistic regression was used to estimate odds ratios (ORs) for mortality.

Results: Of the patients, 54% were discharged, 17% left against medical advice, and 29% died. Higher mortality was associated with increased TBSA, elevated Baux scores, full-thickness burns, respiratory complications, and critical care needs. Flame burns accounted for 63% of injuries, and TBSA >60% was linked to 90% mortality. Logistic regression showed inhalation injury increased mortality risk (OR=8.475), whereas male gender was protective (OR=0.219). Female mortality (39.58%) was more than twice that of males (18.27%). Age was not independently associated with mortality. Children under 5 mainly died from scald burns and early infections, whereas older adults primarily died from extensive TBSA burns and comorbidities.

Conclusions: Burn injuries in Pakistan carry substantial mortality, particularly among women and children. Prevention strategies, early intervention, and gender- and age-sensitive clinical approaches are needed to reduce disparities and improve survival.

烧伤流行病学和结果差异:巴基斯坦烧伤住院患者的研究
目的:调查巴基斯坦烧伤住院患者的人口学、临床和结局差异,重点关注与死亡率相关的性别、年龄和烧伤特征。方法:本回顾性研究分析了2022年巴基斯坦拉瓦尔品第圣家医院收治的389例烧伤患者的数据。变量包括年龄、性别、烧伤病因、烧伤总体表面积(TBSA)、合并症和临床结果。统计分析确定了这些因素与患者预后之间的关联。使用二元逻辑回归来估计死亡率的优势比(ORs)。结果:54%的患者出院,17%的患者不遵医嘱离开,29%的患者死亡。较高的死亡率与TBSA升高、Baux评分升高、全层烧伤、呼吸系统并发症和重症监护需求相关。火焰烧伤占63%的伤害,60%的TBSA与90%的死亡率有关。Logistic回归显示吸入性损伤增加死亡风险(OR=8.475),而男性具有保护作用(OR=0.219)。女性死亡率(39.58%)是男性死亡率(18.27%)的两倍多。年龄与死亡率没有独立的关系。5岁以下儿童主要死于烫伤和早期感染,而老年人主要死于大面积TBSA烧伤和合并症。结论:巴基斯坦的烧伤死亡率很高,尤其是妇女和儿童。需要采取预防策略、早期干预和对性别和年龄敏感的临床方法来减少差异和提高生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Advances in Skin & Wound Care
Advances in Skin & Wound Care DERMATOLOGY-NURSING
CiteScore
2.50
自引率
12.50%
发文量
271
审稿时长
>12 weeks
期刊介绍: A peer-reviewed, multidisciplinary journal, Advances in Skin & Wound Care is highly regarded for its unique balance of cutting-edge original research and practical clinical management articles on wounds and other problems of skin integrity. Each issue features CME/CE for physicians and nurses, the first journal in the field to regularly offer continuing education for both disciplines.
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