Jonathan Parra, Marla I Macias-Contreras, Dulce G Guillén Matus, Katherine R Duncan
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引用次数: 0
Abstract
Covering: This review covers literature from 2015 to present.It is widely recognised that there is a significant gap between bacterial natural product potential and detected/described products. As such, there are several recent reviews on elicitation strategies for natural products discovery, which are often laboratory focused. Recently, a move to more ecology-focused approaches to understand the function of metabolites in nature and what impacts expression has been a growing trend. In this review, we aim to capture work done that goes beyond laboratory conditions and address ecological studies focussed on what impacts bacterial chemistry, covering both abiotic and biotic influences. We aim to touch on the impact of biodiversity loss, changes in ecosystems and future climate parameters and the implications this will have on natural products chemistry and biodiscovery efforts, the scale and consequences of which are not known.
期刊介绍:
Natural Product Reports (NPR) serves as a pivotal critical review journal propelling advancements in all facets of natural products research, encompassing isolation, structural and stereochemical determination, biosynthesis, biological activity, and synthesis.
With a broad scope, NPR extends its influence into the wider bioinorganic, bioorganic, and chemical biology communities. Covering areas such as enzymology, nucleic acids, genetics, chemical ecology, carbohydrates, primary and secondary metabolism, and analytical techniques, the journal provides insightful articles focusing on key developments shaping the field, rather than offering exhaustive overviews of all results.
NPR encourages authors to infuse their perspectives on developments, trends, and future directions, fostering a dynamic exchange of ideas within the natural products research community.