Comparative Evaluation of Mineral Trioxide Aggregate, Biodentine, and Calcium Hydroxide for Apical Closure in Nonvital Immature Teeth: A Randomized Controlled Trial.
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Abstract
Background: Managing nonvital immature teeth with open apices poses clinical challenges, particularly in achieving predictable apical closure.
Aim: To compare the efficacy of mineral trioxide aggregate (MTA), Biodentine, and calcium hydroxide in promoting apical closure in nonvital immature anterior teeth.
Materials and methods: This randomized controlled trial involved 60 patients aged 8-14 years with nonvital immature maxillary anterior teeth. Participants were divided into three groups: group I-MTA, group II-Biodentine, and group III-calcium hydroxide. Standardized treatment protocols were followed, and radiographic assessments were conducted at baseline, 3 months, 6 months, and 12 months to evaluate apical closure.
Results: Group I (MTA) and group II (Biodentine) demonstrated significantly faster apical closure than group III (calcium hydroxide) (p < 0.05). Biodentine showed superior outcomes in achieving complete root-end closure within 6 months.
Conclusion: Biodentine is an effective material for promoting faster apical closure in nonvital immature teeth, followed closely by MTA. Calcium hydroxide required a longer duration to achieve comparable results.
How to cite this article: Sabu A, Ramesh R. Comparative Evaluation of Mineral Trioxide Aggregate, Biodentine, and Calcium Hydroxide for Apical Closure in Nonvital Immature Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2026;19(5):575-587.
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