The Impact of Bone Cement Distribution in Unilateral PVP on Therapeutic Outcomes of Vertebral Compression Fracture Repair.

IF 2 Q2 ORTHOPEDICS
Orthopedic Research and Reviews Pub Date : 2026-06-08 eCollection Date: 2026-01-01 DOI:10.2147/ORR.S567335
Alimujiang Yusufu, Parhat Yasin, Abuduwupuer Haibier, Yuan Ma
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引用次数: 0

Abstract

Background: Osteoporotic vertebral compression fractures (OVCFs) are common in the elderly, severely impacting health and quality of life. Percutaneous vertebroplasty (PVP) is a primary treatment, with bone cement distribution being a key factor influencing its efficacy.

Objective: This study aimed to evaluate the impact of bone cement distribution patterns on clinical outcomes in unilateral PVP for OVCFs.

Methods: A total of 145 patients undergoing first-time unilateral PVP were retrospectively analyzed. Based on postoperative anteroposterior X-rays, patients were divided into three groups according to cement coverage: Group A (uniform distribution across three vertebral regions, n=57), Group B (covering >1/2 to ≤2/3, n=51), and Group C (covering >1/3 to ≤1/2, n=37). Primary outcomes (VAS, ODI, vertebral height recovery, refracture rate) and secondary outcomes were compared.

Results: At one-year follow-up, VAS scores were significantly lower in Groups A (2.12±0.54) and B (2.16±0.54) than in Group C (2.43±0.50, P<0.05). Vertebral height recovery was superior in Groups A and B compared to Group C (P<0.05). The overall refracture rate was significantly lower in Group A (3.6%) than in Group C (18.9%, P<0.05), with no significant difference from Group B (3.9%). Group A received a higher cement volume (4.95±0.43 mL) than Groups B and C (P<0.05).

Conclusion: Bone cement distribution crossing the vertebral midline is associated with better pain relief, improved vertebral height restoration, and a lower refracture rate after unilateral PVP. However, exceeding two-thirds vertebral coverage does not appear to be a critical factor for surgical efficacy.

单侧PVP骨水泥分布对椎体压缩性骨折修复疗效的影响。
背景:骨质疏松性椎体压缩性骨折(OVCFs)在老年人中很常见,严重影响健康和生活质量。经皮椎体成形术(PVP)是主要的治疗方法,骨水泥分布是影响其疗效的关键因素。目的:本研究旨在评估骨水泥分布模式对OVCFs单侧PVP临床结果的影响。方法:对145例首次单侧PVP患者进行回顾性分析。根据术后正位x线片,根据骨水泥覆盖情况将患者分为三组:A组(均匀分布在三个椎体区域,n=57), B组(覆盖>1/2至≤2/3,n=51), C组(覆盖>1/3至≤1/2,n=37)。比较主要结局(VAS、ODI、椎体高度恢复、再骨折率)和次要结局。结果:随访1年,A组VAS评分(2.12±0.54)、B组VAS评分(2.16±0.54)明显低于C组(2.43±0.50)。结论:骨水泥沿椎体中线分布能更好地缓解疼痛,改善椎体高度恢复,降低单侧PVP术后再骨折率。然而,超过三分之二的椎体覆盖似乎并不是手术疗效的关键因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Orthopedic Research and Reviews
Orthopedic Research and Reviews Medicine-Orthopedics and Sports Medicine
CiteScore
2.80
自引率
0.00%
发文量
51
审稿时长
16 weeks
期刊介绍: Orthopedic Research and Reviews is an international, peer-reviewed, open-access journal focusing on the patho-physiology of the musculoskeletal system, trauma, surgery and other corrective interventions to restore mobility and function. Advances in new technologies, materials, techniques and pharmacological agents will be particularly welcome. Specific topics covered in the journal include: Patho-physiology and bioengineering, Technologies and materials science, Surgical techniques, including robotics, Trauma management and care, Treatment including pharmacological and non-pharmacological, Rehabilitation and Multidisciplinarian care approaches, Patient quality of life, satisfaction and preference, Health economic evaluations. The journal welcomes submitted papers covering original research, basic science and technology, clinical studies, reviews and evaluations, guidelines, expert opinion and commentary, case reports and extended reports.
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