Caracterización del inicio de la nutrición en pacientes con soporte vasopresor en cuidado intensivo: un estudio retrospectivo de un centro de alta complejidad en la ciudad de Medellín

Acta Colombiana de Cuidado Intensivo Pub Date : 2026-04-01 Epub Date: 2026-03-03 DOI:10.1016/j.acci.2026.100591
Mario Andrés Sfeir Moreno , Adrián Valverde Legarda , Bladimir Alejandro Gil Valencia , Francisco José Molina Saldarriaga , Juan Carlos Zuluaga Serna , Néstor Sfeir Moreno
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Abstract

Introduction

The initiation of nutritional support in patients with shock represents a challenge in the intensive care unit. Despite the availability of clinical practice guidelines, the available evidence varies and limits precise recommendations regarding the timing, route of administration and initial dose of nutritional support.

Methods

An analytical study was conducted from a retrospective cohort of adult patients diagnosed with shock and treated between January 2023 and January 2025 at a high complexity institution in Medellin, Colombia. Characteristics of nutritional support initiation and clinical outcomes were described. Multivariate logistic regression analysis was performed to evaluate associations.

Results

Enteral nutrition was administered to 88.6% of patients, and in-hospital mortality was 30.4%. In multivariable analysis, age, use of vasopressin, and parenteral nutrition were associated with higher mortality; in addition, initiation of nutrition at 6-12 hours or after 24 hours, as well as a caloric intake of 21-25 kcal/kg/day, were associated with a higher risk compared with initiation at 13-24 hours and caloric intake of 11-15 kcal/kg/day. Nutrition-related complications occurred in 11% of cases.

Conclusion

In patients with shock, enteral nutrition can be considered after achieving adequate hemodynamic stability following resuscitation; initiation is safer when avoiding premature initiation or unjustified delays, with progressive caloric prescription according to clinical evolution.
在重症监护中使用血管加压药物的患者开始营养的特征:Medellin市一个高度复杂中心的回顾性研究
在重症监护病房中,休克患者的营养支持是一个挑战。尽管有临床实践指南,但现有的证据各不相同,限制了关于营养支持的时间、给药途径和初始剂量的精确建议。方法对2023年1月至2025年1月在哥伦比亚麦德林一家高复杂性医院诊断为休克并接受治疗的成年患者进行回顾性队列研究。描述了营养支持开始的特点和临床结果。采用多变量logistic回归分析来评估相关性。结果88.6%的患者接受了肠外营养,住院死亡率为30.4%。在多变量分析中,年龄、抗利尿激素的使用和肠外营养与较高的死亡率相关;此外,在6-12小时或24小时后开始营养,以及21-25千卡/公斤/天的热量摄入,与13-24小时开始营养和11-15千卡/公斤/天的热量摄入相比,风险更高。11%的病例出现营养相关并发症。结论休克患者复苏后血液动力学稳定后可考虑肠内营养;当避免过早启动或不合理的延迟时,启动是更安全的,根据临床进展进行渐进式热量处方。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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