Predicting Primary Stability of Stemless TSA From Preoperative Bone Density and Surgical Factors

IF 2.4 3区 医学 Q2 ORTHOPEDICS
Ingmar Fleps, Ghislain Maquer, Kyle Snethen, Christine Mueri, Taku Hatta, Jeff Bischoff, Philippe Favre
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Abstract

This study investigated how preoperative bone quality, patient and implant factors can predict the primary stability of a stemless humeral component in total shoulder arthroplasty (TSA). Thirty‑one cadaveric humeri were CT‑scanned with a calibration phantom, and trabecular bone density within the metaphysis was quantified. Specimens were implanted and subjected to cyclic loading at 500 N and 870 N along physiologically representative directions and implant‑to‑bone micromotion was measured using motion capture. Generalized linear models were developed to predict implant micromotion based on patient and implant size factors, including age, height, weight, gender, ethnicity, cancer history, chemotherapy status, apparent peri-implant density, anchor size, head size, resection angle, and load level. Micromotion was significantly larger at 870 N than at 500 N, and males exhibited significantly lower micromotion than females, consistent with the associated higher bone density and larger implant sizes. Peri‑implant density was the strongest individual predictor explaining 34% of micromotion variation. Model predictions went up 49% of micromotion variation if load level was accounted for. Adding anchor and head sizes markedly improved this predictive power to 71%, which outperformed models incorporating patient height and gender (67%). Moderate improvement (73%) was seen when density, load level, height, gender, and anchor size were included after automatic backward selection. These findings demonstrate that bone density only partially predicts primary stability of anatomic stemless shoulder arthroplasty, and that incorporating implant sizing substantially improves predictive accuracy. This preoperative information can provide a more objective and consistent identification of patients with adequate bone quality for stemless fixation.

从术前骨密度和手术因素预测无茎TSA的初级稳定性。
本研究探讨了术前骨质量、患者和植入物因素如何预测全肩关节置换术(TSA)中无柄肱骨假体的初始稳定性。对31例肱骨尸体进行CT扫描,并对干骺端内的骨小梁骨密度进行量化。将标本植入并沿生理代表性方向在500 N和870 N下进行循环加载,并使用运动捕捉技术测量植入物到骨的微运动。基于患者和种植体大小因素,包括年龄、身高、体重、性别、种族、癌症史、化疗状况、种植体周围表观密度、锚定大小、头大小、切除角度和负荷水平,建立了广义线性模型来预测种植体微动。870 N时的微动明显大于500 N,且雄性的微动明显低于雌性,这与较高的骨密度和较大的种植体尺寸相一致。种植体周围密度是最强的个体预测因子,可以解释34%的微动变异。如果考虑到负荷水平,模型对微动变化的预测提高了49%。添加锚点和头部尺寸显著提高了预测能力,达到71%,优于纳入患者身高和性别的模型(67%)。在自动逆向选择后,当包括密度、负荷水平、高度、性别和锚尺寸时,可以看到中度改善(73%)。这些研究结果表明,骨密度只能部分预测解剖无柄肩关节置换术的初级稳定性,而结合植入物的大小可以大大提高预测的准确性。这些术前信息可以提供更客观和一致的鉴定患者是否有足够的骨质量进行无茎固定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Orthopaedic Research®
Journal of Orthopaedic Research® 医学-整形外科
CiteScore
6.10
自引率
3.60%
发文量
261
审稿时长
3-6 weeks
期刊介绍: The Journal of Orthopaedic Research is the forum for the rapid publication of high quality reports of new information on the full spectrum of orthopaedic research, including life sciences, engineering, translational, and clinical studies.
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