Cervical tuberculosis mimicking carcinoma of the cervix in a patient with long-standing secondary amenorrhea.

Abstract

Background: Tuberculosis remains a significant cause of extrapulmonary disease in endemic regions. Genital tuberculosis most commonly affects the fallopian tubes and endometrium, while cervical involvement is rare. Presentation as a cervical mass is particularly uncommon and may closely mimic cervical cancer, leading to diagnostic challenges.

Case: We report a case of a woman in her 40s with a history of long-standing secondary amenorrhea for 12 years who presented with postcoital bleeding. Clinical examination revealed a cervical growth. Histopathological evaluation of the cervical biopsy demonstrated inflammation with granulomas, no evidence of malignancy was identified. The tissue was positive for ZN stain and MGIT.

Management and outcome: The patient was initiated on standard anti-tubercular therapy for 6 months. Patient had resolution of symptoms and interval reduction in cervical lesion at 6 months follow-up.

Conclusion: Cervical tuberculosis, though rare, should be considered in the differential diagnosis of suspected carcinoma cervix, particularly in patients from endemic areas.