Descriptive analysis of routine childhood vaccination coverage of selected vaccines in Nigeria (1980-2023) using the Global Burden of Disease Study (2023).

IF 4.2 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Human Vaccines & Immunotherapeutics Pub Date : 2026-12-01 Epub Date: 2026-06-08 DOI:10.1080/21645515.2026.2684092
Adewunmi Akingbola, Abiodun Adegbesan, Olajumoke Adewole, Nwaeze Emmanuel, Opeyemi Joshua Alabi, Petra Mariaria
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引用次数: 0

Abstract

Routine childhood immunization remains an effective public health intervention for reducing childhood morbidity and mortality from vaccine-preventable diseases. This study examined trends in routine childhood vaccination coverage in Nigeria from 1980 to 2023. We conducted a retrospective secondary descriptive analysis using routine childhood vaccination coverage estimates from the Global Burden of Disease Study 2023. Annual national coverage estimates for BCG, DTP3, Polio3, MCV1, and HepB3 vaccines were analyzed from 1980 to 2023. Temporal trends were assessed using line plots and forest plots with associated 95% uncertainty intervals, and the highest and lowest performing years for each vaccine were identified. Coverage for all assessed vaccines was lowest in 1980, followed by gradual expansion during the late 1980s and early 1990s, stagnation between the mid-1990s and early 2000s, and improvement after 2005. Peak coverage occurred between 2019 and 2021 for most vaccines, with BCG reaching the highest in 2021 at 73.6% (95% UI: 64.7-78.3). However, no vaccine achieved the WHO target of 90% national coverage throughout the study period. Although Nigeria has made measurable progress in routine childhood immunization over four decades, coverage remains below optimal levels, highlighting the need for targeted and equitable immunization strategies.

使用全球疾病负担研究(2023)对尼日利亚(1980-2023)选定疫苗的常规儿童疫苗接种覆盖率进行描述性分析。
常规儿童免疫接种仍然是一项有效的公共卫生干预措施,可降低疫苗可预防疾病造成的儿童发病率和死亡率。本研究调查了1980年至2023年尼日利亚儿童常规疫苗接种覆盖率的趋势。我们使用2023年全球疾病负担研究中的常规儿童疫苗接种覆盖率估算值进行了回顾性二级描述性分析。分析了1980年至2023年卡介苗、百白破、脊髓灰质炎、MCV1和HepB3疫苗的年度全国覆盖率估计数。使用线形图和具有95%不确定区间的森林图评估时间趋势,并确定每种疫苗的最高和最低表现年份。所有评估疫苗的覆盖率在1980年最低,随后在1980年代末和1990年代初逐渐扩大,在1990年代中期和2000年代初停滞不前,2005年之后有所改善。大多数疫苗的覆盖率高峰发生在2019年至2021年之间,卡介苗在2021年达到最高,为73.6% (95% UI: 64.7-78.3)。然而,在整个研究期间,没有疫苗达到世卫组织90%全国覆盖率的目标。尽管40年来尼日利亚在常规儿童免疫方面取得了可衡量的进展,但覆盖率仍低于最佳水平,这突出表明需要制定有针对性和公平的免疫战略。
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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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