Benign Bronchial Tumours: A Rare Case of Endobronchial Fibroma With Hilar-Mediastinal Lymphadenopathy.

Q4 Medicine
Case Reports in Pulmonology Pub Date : 2026-06-02 eCollection Date: 2026-01-01 DOI:10.1155/crpu/8730962
Giuseppina Marrazzo, Teresa Ferrazzo, Giuseppe Failla, Francesco Giuseppe Tropea, Nicola Montenegro, Gianluca Ippolito, Fabio Alfredo Nania, Carlo Gentile, Annamaria Lavecchia, Corrado Pelaia, Girolamo Pelaia
{"title":"Benign Bronchial Tumours: A Rare Case of Endobronchial Fibroma With Hilar-Mediastinal Lymphadenopathy.","authors":"Giuseppina Marrazzo, Teresa Ferrazzo, Giuseppe Failla, Francesco Giuseppe Tropea, Nicola Montenegro, Gianluca Ippolito, Fabio Alfredo Nania, Carlo Gentile, Annamaria Lavecchia, Corrado Pelaia, Girolamo Pelaia","doi":"10.1155/crpu/8730962","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Endobronchial fibroma is a rare benign tumour that can mimic lung cancer, especially when accompanied by airway obstruction and hilar-mediastinal lymphadenopathy.</p><p><strong>Case presentation: </strong>A 73-year-old man under radiological surveillance for pulmonary nodules developed interval growth of a middle-lobe nodule with new hilar-mediastinal lymphadenopathy and an obstructing B4 endobronchial mass. Bronchoscopy revealed a smooth, firm, rubbery polypoid lesion. Tissue sampling included fine-needle aspiration of the endobronchial mass and EBUS-TBNA of nodal stations (7, 11Ri and 11 L). Histology showed fibromatous tissue without atypia; lymph nodes exhibited inflammatory changes. The lesion was fully removed via rigid bronchoscopy with forceps and laser, leading to symptom relief and planned radiological follow-up. We propose a stepwise evaluation pathway for endobronchial tumours when lymphadenopathy is present, highlight pathology features that distinguish fibroma from malignant and benign mimickers and outline practical considerations for bronchoscopic resection.</p><p><strong>Conclusion: </strong>In patients with concurrent endobronchial mass and lymphadenopathy, a targeted approach using EBUS-TBNA can exclude nodal metastasis and support definitive, minimally invasive treatment, potentially avoiding unnecessary surgery.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2026 ","pages":"8730962"},"PeriodicalIF":0.0000,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13239039/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Pulmonology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crpu/8730962","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Endobronchial fibroma is a rare benign tumour that can mimic lung cancer, especially when accompanied by airway obstruction and hilar-mediastinal lymphadenopathy.

Case presentation: A 73-year-old man under radiological surveillance for pulmonary nodules developed interval growth of a middle-lobe nodule with new hilar-mediastinal lymphadenopathy and an obstructing B4 endobronchial mass. Bronchoscopy revealed a smooth, firm, rubbery polypoid lesion. Tissue sampling included fine-needle aspiration of the endobronchial mass and EBUS-TBNA of nodal stations (7, 11Ri and 11 L). Histology showed fibromatous tissue without atypia; lymph nodes exhibited inflammatory changes. The lesion was fully removed via rigid bronchoscopy with forceps and laser, leading to symptom relief and planned radiological follow-up. We propose a stepwise evaluation pathway for endobronchial tumours when lymphadenopathy is present, highlight pathology features that distinguish fibroma from malignant and benign mimickers and outline practical considerations for bronchoscopic resection.

Conclusion: In patients with concurrent endobronchial mass and lymphadenopathy, a targeted approach using EBUS-TBNA can exclude nodal metastasis and support definitive, minimally invasive treatment, potentially avoiding unnecessary surgery.

良性支气管肿瘤:支气管内纤维瘤合并肺门纵隔淋巴结病1例。
背景:支气管内纤维瘤是一种罕见的类似肺癌的良性肿瘤,特别是当伴有气道阻塞和肺门纵隔淋巴结病变时。病例介绍:一名73岁男性,在接受肺结节放射学检查时,发现肺中叶结节间期生长,伴有新的肺门纵隔淋巴结病变和B4支气管内阻塞肿块。支气管镜检查示光滑、坚硬、橡胶状息肉样病变。组织取样包括细针穿刺支气管内肿物和淋巴结站EBUS-TBNA(7、11 ri和11 L)。组织学表现为纤维瘤组织,无异型性;淋巴结出现炎性改变。病变通过硬支气管镜用镊子和激光完全切除,导致症状缓解和计划的放射随访。当存在淋巴结病变时,我们提出了支气管内肿瘤的逐步评估途径,强调了区分纤维瘤与恶性和良性模拟物的病理特征,并概述了支气管镜切除的实际考虑因素。结论:对于并发支气管内肿块和淋巴结病变的患者,采用EBUS-TBNA靶向治疗可以排除淋巴结转移,支持明确的微创治疗,可能避免不必要的手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Case Reports in Pulmonology
Case Reports in Pulmonology Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.80
自引率
0.00%
发文量
23
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书