Utility of Cytopathology in Diagnosing a Plethora of Fungal Infections.

IF 0.7 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Journal of Cytology Pub Date : 2026-01-01 Epub Date: 2026-02-26 DOI:10.4103/joc.joc_43_25

Priya Suneja, Preeti Diwaker, Akanksha Agrawal, Karishma Ranjan, Sonal Sharma, Vinod K Arora, Jolly Rohatgi, Archana Singal

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引用次数: 0

Abstract

Background: Fine-needle aspiration cytology (FNAC) is a simple and reliable technique for diagnosing various inflammatory lesions. Some of these lesions are caused by fungal organisms, which are often missed clinically and thus remain untreated. Most of these infections require prompt diagnosis as they respond to early treatment, and delayed diagnosis may lead to unnecessary complications.

Aim: To study the clinico-cytomorphological spectrum of fungal infections in a tertiary care center.

Materials and methods: This is a retrospective study and includes a total of 25 cases of various fungal infections diagnosed on FNAC over 5 years. Clinical details of these cases were retrieved from cytopathology records, and cytomorphological features were studied in detail.

Results: All 25 cases were analyzed and included rhino-orbital cerebral mucormycosis (15), histoplasmosis (1), cryptococcosis (1), phaeohyphomycosis (1), and aspergillosis (1), along with six cases broadly classified as fungal abscesses.

Conclusion: FNAC is an efficient and unswerving tool, helpful in diagnosing a plethora of fungal infections, especially in clinically unsuspected cases, and thereby facilitates early diagnosis and appropriate treatment.

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细胞病理学在诊断大量真菌感染中的应用。

背景：细针穿刺细胞学（FNAC）是诊断各种炎性病变的一种简单可靠的技术。其中一些病变是由真菌引起的，通常在临床上被忽视，因此没有得到治疗。这些感染大多需要及时诊断，因为它们对早期治疗有反应，而延迟诊断可能导致不必要的并发症。目的：探讨某三级保健中心真菌感染的临床细胞形态学特征。材料与方法：本研究是一项回顾性研究，共纳入5年来诊断为FNAC的各种真菌感染25例。从细胞病理学记录中检索这些病例的临床细节，并详细研究了细胞形态学特征。结果：对25例病例进行分析，包括鼻眶脑毛霉病（15例）、组织胞浆菌病（1例）、隐球菌病（1例）、褐丝霉病（1例）、曲霉病（1例），以及6例真菌脓肿。结论：FNAC是一种高效、可靠的诊断工具，有助于诊断大量真菌感染，特别是临床未发现的病例，从而促进早期诊断和适当治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cytology MEDICAL LABORATORY TECHNOLOGY-

CiteScore

1.80

自引率

7.70%

发文量

审稿时长

46 weeks

期刊介绍： The Journal of Cytology is the official Quarterly publication of the Indian Academy of Cytologists. It is in the 25th year of publication in the year 2008. The journal covers all aspects of diagnostic cytology, including fine needle aspiration cytology, gynecological and non-gynecological cytology. Articles on ancillary techniques, like cytochemistry, immunocytochemistry, electron microscopy, molecular cytopathology, as applied to cytological material are also welcome. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews, meta-analysis, and debates.