Interruption in treatment and its risk factors among adults living with HIV in Uganda: a cross-sectional study.

IF 2.8 4区医学 Q3 INFECTIOUS DISEASES

AIDS Research and Therapy Pub Date : 2026-06-07 DOI:10.1186/s12981-026-00898-x

Saadick Mugerwa Ssentongo, William Okello, Hamidah Kakooza Mulungi, Peter Sekiranda, Christine Ninsiima, Bonniface Oryokot

引用次数: 0

Abstract

Background: This study aimed to determine the prevalence of Interruption in treatment (IIT) and its risk factors in Katakwi District, Uganda.

Methods: A cross-sectional study was conducted in three antiretroviral therapy clinics. Poisson generalized estimating equations were used to identify factors associated with interruption in treatment.

Results: IIT was high at 68.2% and was associated with being aged 25-49, lacking social support from family and friends, being on ART for 0-1 years, and having a non-suppressed viral load. However, lower IIT rates were observed among those living within 5 km of the facility.

Conclusion: There is a need to strengthen client-tracking systems and client-adherence literacy to reduce this IIT.

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乌干达成人艾滋病毒感染者治疗中断及其危险因素：一项横断面研究。

背景：本研究旨在确定乌干达Katakwi地区治疗中断（IIT）的患病率及其危险因素。方法：在三个抗逆转录病毒治疗诊所进行横断面研究。使用泊松广义估计方程来确定与治疗中断相关的因素。结果：IIT高68.2%，与年龄25-49岁，缺乏家庭和朋友的社会支持，接受ART治疗0-1年，病毒载量未抑制有关。然而，居住在该设施5公里范围内的人的IIT率较低。结论：有必要加强客户跟踪系统和客户依从性素养，以减少这种IIT。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AIDS Research and Therapy INFECTIOUS DISEASES-

CiteScore

3.80

自引率

4.50%

发文量

审稿时长

16 weeks

期刊介绍： AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered