Abda Ramírez-Echavarría, Daniel Sat-Muñoz, Luz Ma Adriana Balderas-Peña, Pedro Mauricio Nuñez-Aviña, Karina Jannet Flores-Rios
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引用次数: 0
Abstract
Background: Paranasal sinus cancer comprises a group of neoplasms with low incidence but high aggressiveness, due to their anatomical location in the center of the face and the significant sequelae caused by both the disease and its treatment. Surgery for maxillary sinus neoplasms is considered potentially curative in early stages; however, maxillectomy is a procedure that requires a high level of surgical skill and represents a challenge for oncologic surgeons.
Objective: To describe overall survival and the outcomes of surgical treatment based on maxillectomy, either as a standalone procedure or in combination with radiosensitizing chemotherapy and/or radiotherapy, in patients treated between 2013 and 2023 at the High Specialty Medical Unit (UMAE), Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social.
Materials and methods: This was a retrospective longitudinal study with follow-up of a series of cases. Descriptive statistical analysis was performed using SPSS version 29 software. Qualitative variables were reported as proportions and percentages, and quantitative variables as means with standard deviation or medians with interquartile ranges.
Results: The 10-year overall survival rate was 55.3% in patients who underwent surgery. Regarding survival specific to the type of surgical procedure performed, segmental resections offered higher survival rates, reaching 61.5% at 10 years and a median survival of 102 months.
Conclusions: The results of the surgical management show local recurrence rates and overall survival comparable to those described in the international literature.
背景:鼻副窦癌是一组发病率低但侵袭性高的肿瘤,因为其解剖位置位于面部中心,且其疾病和治疗均有显著的后遗症。手术治疗上颌窦肿瘤在早期被认为是可以治愈的;然而,上颌切除术是一项需要高水平手术技巧的手术,对肿瘤外科医生来说是一项挑战。目的:描述2013年至2023年间在高等专科医疗单位(UMAE)、Hospital de Especialidades、Centro m dico Nacional de Occidente、Instituto Mexicano del Seguro Social接受治疗的患者中,上颌切除术作为单独手术或联合放射增敏化疗和/或放疗的总体生存率和手术治疗结果。材料与方法:本研究为回顾性纵向研究,随访了一系列病例。采用SPSS 29版软件进行描述性统计分析。定性变量报告为比例和百分比,定量变量报告为带有标准差的平均值或带有四分位数范围的中位数。结果:手术患者10年总生存率为55.3%。就特定手术类型的生存率而言,节段性切除术提供了更高的生存率,10年达到61.5%,中位生存期为102个月。结论:手术处理的结果显示局部复发率和总生存率与国际文献中描述的相当。