{"title":"Reference values for Japanese fetal penile length.","authors":"Toshiyuki Hata, Yume Takahashi, Miyu Konishi, Aya Koyanagi, Yasunari Miyagi, Takahito Miyake","doi":"10.1007/s10396-026-01651-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To determine reference values for Japanese fetal penile length using ultrasonography at 18-21 + 6 as well as 28-31 + 5 weeks of gestation.</p><p><strong>Methods: </strong>Three hundred and five pregnant women were enrolled in the study, and fetal penile length was measured at both 18-21 + 6 and 28-31 + 5 weeks of gestation. All 305 fetuses were successfully measured. Outer penile length (OPL) of the male fetus was measured, and OPL reference values were determined. Intra- and inter-observer agreements regarding OPL were also assessed with Bland-Altman plots and intra- and inter-correlation coefficients.</p><p><strong>Results: </strong>OPL showed an increasing trend with advancing gestation at 18-21 + 6 (r = 0.2757, p < 0.001) and 28-31 + 5 (r = 0.2306, p < 0.001) weeks. Intra- and inter-reproducibilities of OPL were excellent. Intra- and inter-correlation coefficients of OPL were 0.982287 and 0.885602, respectively, at 18-21 + 6 weeks, and 0.994104 and 0.97343, respectively, at 28-31 + 5 weeks.</p><p><strong>Conclusion: </strong>Our results provide reference values for Japanese fetal penile length, which may promote accurate prenatal diagnoses of hypospadias, micropenis, and buried penis in Japan.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Ultrasonics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10396-026-01651-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To determine reference values for Japanese fetal penile length using ultrasonography at 18-21 + 6 as well as 28-31 + 5 weeks of gestation.
Methods: Three hundred and five pregnant women were enrolled in the study, and fetal penile length was measured at both 18-21 + 6 and 28-31 + 5 weeks of gestation. All 305 fetuses were successfully measured. Outer penile length (OPL) of the male fetus was measured, and OPL reference values were determined. Intra- and inter-observer agreements regarding OPL were also assessed with Bland-Altman plots and intra- and inter-correlation coefficients.
Results: OPL showed an increasing trend with advancing gestation at 18-21 + 6 (r = 0.2757, p < 0.001) and 28-31 + 5 (r = 0.2306, p < 0.001) weeks. Intra- and inter-reproducibilities of OPL were excellent. Intra- and inter-correlation coefficients of OPL were 0.982287 and 0.885602, respectively, at 18-21 + 6 weeks, and 0.994104 and 0.97343, respectively, at 28-31 + 5 weeks.
Conclusion: Our results provide reference values for Japanese fetal penile length, which may promote accurate prenatal diagnoses of hypospadias, micropenis, and buried penis in Japan.
期刊介绍:
The Journal of Medical Ultrasonics is the official journal of the Japan Society of Ultrasonics in Medicine. The main purpose of the journal is to provide forum for the publication of papers documenting recent advances and new developments in the entire field of ultrasound in medicine and biology, encompassing both the medical and the engineering aspects of the science.The journal welcomes original articles, review articles, images, and letters to the editor.The journal also provides state-of-the-art information such as announcements from the boards and the committees of the society.