Global, regional, and national burden of depression among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021

IF 3.2 3区医学 Q2 PSYCHIATRY

Archives of Women's Mental Health Pub Date : 2026-06-04 DOI:10.1007/s00737-026-01714-1

Jingjing Sun, Wenyue Xu, Guanghua Zhang, Panpan Li

{"title":"Global, regional, and national burden of depression among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021","authors":"Jingjing Sun, Wenyue Xu, Guanghua Zhang, Panpan Li","doi":"10.1007/s00737-026-01714-1","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p>Depression is a common mental disorder, particularly among women of childbearing age (WCBA). There is a lack of comprehensive epidemiological analysis on the longitudinal trends and changing patterns of depression in WCBA.</p><h3>Methods</h3><p>The study utilized data obtained from the Global Burden of Disease (GBD) 2021 database to analyze incidence, prevalence, and years lived with disability (YLDs) of depression among WCBA across regions, age groups, and sociodemographic index (SDI). We also examined temporal trends, driving factors, age patterns, and projections up to 2035.</p><h3>Results</h3><p>Globally, from 1990 to 2021, the incidence rate increased by 17.65% (95% UI, 13.51 to 21.84), prevalence rate by 15.00% (95% UI, 11.53 to 18.39), and YLDs rate by 16.03% (95% UI, 12.39 to 19.86). Among the five SDI regions, the highest EAPCs were observed in the high SDI regions for incidence rate (0.49; 95% UI, 0.26 to 0.72), prevalence rate (0.33; 95% UI,0.15 to0.50), and YLDs rate (0.40; 95% CI, 0.20 to 0.60). Regionally, a U-shaped association was found between the SDI and rate of incidence, prevalence, and YLDs. Nationally, Greenland reported the highest rates of three indicators in 2021, whereas Mexico exhibited the largest growth over time. This study found that the 15—19 age group showed a particularly severe new burden of depression among WCBA in 2021, especially in high SDI. The highest burden of depression among WCBA was reported in the older age groups such as 40—44 and 45—49 age groups. Population growth and epidemiological change were the primary drivers of this change except in low SDI which aging was the primary driver. Our study predictions suggested that the burden of depression among WCBA will continue to grow in the future.</p><h3>Conclusions</h3><p>Overall, the burden of depression among WCBA has significantly increased globally over the past 32 years, particularly in high SDI regions and among the 15—19 age group. The findings underscore the need for tailored interventions to control the projected rise burden of depression among WCBA.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Women's Mental Health","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00737-026-01714-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose

Depression is a common mental disorder, particularly among women of childbearing age (WCBA). There is a lack of comprehensive epidemiological analysis on the longitudinal trends and changing patterns of depression in WCBA.

Methods

The study utilized data obtained from the Global Burden of Disease (GBD) 2021 database to analyze incidence, prevalence, and years lived with disability (YLDs) of depression among WCBA across regions, age groups, and sociodemographic index (SDI). We also examined temporal trends, driving factors, age patterns, and projections up to 2035.

Results

Globally, from 1990 to 2021, the incidence rate increased by 17.65% (95% UI, 13.51 to 21.84), prevalence rate by 15.00% (95% UI, 11.53 to 18.39), and YLDs rate by 16.03% (95% UI, 12.39 to 19.86). Among the five SDI regions, the highest EAPCs were observed in the high SDI regions for incidence rate (0.49; 95% UI, 0.26 to 0.72), prevalence rate (0.33; 95% UI,0.15 to0.50), and YLDs rate (0.40; 95% CI, 0.20 to 0.60). Regionally, a U-shaped association was found between the SDI and rate of incidence, prevalence, and YLDs. Nationally, Greenland reported the highest rates of three indicators in 2021, whereas Mexico exhibited the largest growth over time. This study found that the 15—19 age group showed a particularly severe new burden of depression among WCBA in 2021, especially in high SDI. The highest burden of depression among WCBA was reported in the older age groups such as 40—44 and 45—49 age groups. Population growth and epidemiological change were the primary drivers of this change except in low SDI which aging was the primary driver. Our study predictions suggested that the burden of depression among WCBA will continue to grow in the future.

Conclusions

Overall, the burden of depression among WCBA has significantly increased globally over the past 32 years, particularly in high SDI regions and among the 15—19 age group. The findings underscore the need for tailored interventions to control the projected rise burden of depression among WCBA.

查看原文本刊更多论文

1990年至2021年育龄妇女抑郁症的全球、区域和国家负担：来自2021年全球疾病负担研究的见解

目的：抑郁症是一种常见的精神障碍，尤其是育龄妇女（WCBA）。目前缺乏对西部西部地区抑郁症的纵向趋势和变化模式的综合流行病学分析。方法：该研究利用来自全球疾病负担（GBD） 2021数据库的数据，分析不同地区、年龄组和社会人口指数（SDI）的WCBA中抑郁症的发病率、患病率和残疾生活年限（YLDs）。我们还研究了时间趋势、驱动因素、年龄模式和到2035年的预测。结果：从1990年到2021年，全球发病率上升17.65% (95% UI, 13.51 ~ 21.84)，患病率上升15.00% (95% UI, 11.53 ~ 18.39)， YLDs率上升16.03% （95% UI, 12.39 ~ 19.86）。在5个SDI区域中，高SDI区域的EAPCs在发病率（0.49,95% UI, 0.26 ~ 0.72）、患病率（0.33,95% UI,0.15 ~ 0.50）和YLDs率（0.40,95% CI, 0.20 ~ 0.60）方面最高。从区域来看，SDI与发病率、患病率和YLDs之间呈u型关系。在全国范围内，格陵兰岛在2021年报告了三项指标的最高增长率，而墨西哥随着时间的推移表现出最大的增长率。本研究发现，在2021年，15-19岁年龄组的WCBA出现了特别严重的新抑郁负担，尤其是在高SDI年龄组。据报道，WCBA中抑郁症负担最高的年龄组为40-44岁和45-49岁年龄组。人口增长和流行病学变化是这一变化的主要驱动因素，但在低SDI地区，老龄化是主要驱动因素。我们的研究预测表明，未来WCBA的抑郁负担将继续增加。结论：总体而言，在过去32年中，全球范围内WCBA的抑郁负担显著增加，特别是在高SDI地区和15-19岁年龄组。研究结果强调，需要有针对性的干预措施来控制WCBA中预期的抑郁负担上升。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Archives of Women's Mental Health 医学-精神病学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.