Pedunculated Pleomorphic Adenoma With Adipocytic Metaplasia of the Hard Palate: A Case Report.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Clinical Medicine Insights. Case Reports Pub Date : 2026-05-28 eCollection Date: 2026-01-01 DOI:10.1177/11795476261457176
Fakhreddine Alouane, Lilia Ben Zid, Oussema Belkacem, Raouaa Belkacem Chebil, Nabiha Douki
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引用次数: 0

Abstract

Background: Salivary gland tumors represent less than 4% of all head and neck tumors, with pleomorphic adenoma (PA) being the most common among them. The palate represents the most frequent site of occurrence. Although typically presenting as a firm and sessile mass, PA may occasionally exhibit unusual clinical or histological features that complicate diagnosis.

Case presentation: We describe an unusual case of a 46-year-old woman presenting with a pedunculated PA of the hard palate, exhibiting superficial ulceration and mild pressure induced bone erosion detected radiographically. The lesion was completely excised under local anesthesia. Histopathological examination confirmed the diagnosis of PA with adipocytic metaplasia, an uncommon finding that may mimic malignant transformation. Healing occurred uneventfully and no recurrence was observed after a 12 month follow up.

Conclusion: This case highlights the importance of recognizing atypical clinical and histological variants of pleomorphic adenoma and establishing an appropriate differential diagnosis. Accurate diagnosis and optimal management require careful correlation of clinical, radiological, and histopathological findings. Long term follow up remains essential to ensure early detection of potential recurrence or malignant transformation.

硬腭带梗多形性腺瘤伴脂肪细胞化生1例。
背景:唾液腺肿瘤在头颈部肿瘤中所占比例不到4%,其中以多形性腺瘤(PA)最为常见。上颚是最常发生的部位。虽然典型表现为坚硬和无根的肿块,但PA偶尔也会表现出不寻常的临床或组织学特征,使诊断复杂化。病例介绍:我们描述了一个不寻常的情况下,46岁的妇女提出了一个带脚的硬腭PA,表现出浅表溃疡和轻度压力引起的骨侵蚀的x线检查。病灶在局部麻醉下完全切除。组织病理学检查证实了PA合并脂肪细胞化生的诊断,这是一种罕见的发现,可能类似恶性转化。术后随访12个月,无复发。结论:本病例强调了识别多形性腺瘤的非典型临床和组织学变异并建立适当的鉴别诊断的重要性。准确的诊断和最佳的管理需要仔细地将临床、放射学和组织病理学的发现联系起来。长期随访仍然是必要的,以确保早期发现潜在的复发或恶性转化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Medicine Insights. Case Reports
Clinical Medicine Insights. Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
1.10
自引率
0.00%
发文量
57
审稿时长
8 weeks
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