“Retinal doughnut”: A characteristic analysis of the retinal large Gaussian curvature annular region

IF 2.7 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2026-06-01 Epub Date: 2026-05-30 DOI:10.1016/j.pdpdt.2026.105532

Jingying Liu , Guoren Xu , Zhen Huang , Ming Yan , Ya Ye , Yanping Song

{"title":"“Retinal doughnut”: A characteristic analysis of the retinal large Gaussian curvature annular region","authors":"Jingying Liu , Guoren Xu , Zhen Huang , Ming Yan , Ya Ye , Yanping Song","doi":"10.1016/j.pdpdt.2026.105532","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>To quantitatively analyze the characteristics of the retinal large Gaussian curvature annular region (RLCA) in myopic patients using ultra-widefield swept-source optical coherence tomography (SS-OCT).</div></div><div><h3>Methods</h3><div>Patients with myopia underwent 24 mm × 20 mm macular OCTA, and retinal curvature (RC) maps were generated. Key RLCA parameters, mean radius (r<sub>mean</sub>) and radial distance (R) from the maximum RC point (RCmax) to the fovea, were quantified and correlated with axial length (AL), RCmax, and central macular retinal curvature (RCc).</div></div><div><h3>Results</h3><div>A total of 68 patients (136 eyes) were included in this study. The r<sub>mean</sub> exhibited a significant negative correlation with both RCmax and RCc. In contrast, no statistically significant correlation was observed between the r<sub>mean</sub> and AL. Furthermore, R showed significant negative correlations with AL, RCmax, and RCc. Notably, r<sub>mean</sub> was strongly and positively correlated with R. Additionally, RCmax demonstrated a significant negative correlation with AL but a significant positive correlation with RCc.</div></div><div><h3>Conclusions</h3><div>The retinal morphology in the “retinal doughnut” region may be associated with the inherent morphological development of the eye to a large extent. Specifically, the smaller eyes exhibited larger RCc and RCmax values along with a smaller r<sub>mean</sub>, whereas the larger eyes showed the opposite pattern. Nevertheless, AL may be associated with local morphological changes within this region, which are mainly reflected in the RCmax area.</div></div>","PeriodicalId":20141,"journal":{"name":"Photodiagnosis and Photodynamic Therapy","volume":"59 ","pages":"Article 105532"},"PeriodicalIF":2.7000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodiagnosis and Photodynamic Therapy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1572100026001997","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/5/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose

To quantitatively analyze the characteristics of the retinal large Gaussian curvature annular region (RLCA) in myopic patients using ultra-widefield swept-source optical coherence tomography (SS-OCT).

Methods

Patients with myopia underwent 24 mm × 20 mm macular OCTA, and retinal curvature (RC) maps were generated. Key RLCA parameters, mean radius (r_mean) and radial distance (R) from the maximum RC point (RCmax) to the fovea, were quantified and correlated with axial length (AL), RCmax, and central macular retinal curvature (RCc).

Results

A total of 68 patients (136 eyes) were included in this study. The r_mean exhibited a significant negative correlation with both RCmax and RCc. In contrast, no statistically significant correlation was observed between the r_mean and AL. Furthermore, R showed significant negative correlations with AL, RCmax, and RCc. Notably, r_mean was strongly and positively correlated with R. Additionally, RCmax demonstrated a significant negative correlation with AL but a significant positive correlation with RCc.

Conclusions

The retinal morphology in the “retinal doughnut” region may be associated with the inherent morphological development of the eye to a large extent. Specifically, the smaller eyes exhibited larger RCc and RCmax values along with a smaller r_mean, whereas the larger eyes showed the opposite pattern. Nevertheless, AL may be associated with local morphological changes within this region, which are mainly reflected in the RCmax area.

查看原文本刊更多论文

“视网膜甜甜圈”：视网膜大高斯曲率环形区域的特征分析。

目的：利用超宽视场扫源光学相干断层扫描（SS-OCT）定量分析近视患者视网膜大高斯曲率环区（RLCA）的特征。方法：对近视患者行24 mm × 20 mm黄斑OCTA，生成视网膜曲率（RC）图。RLCA的关键参数，平均半径（rmean）和从最大RC点（RCmax）到中央凹的径向距离(R)被量化，并与轴向长度（AL）、RCmax和中央黄斑视网膜曲率（RCc）相关。结果：共纳入68例患者（136只眼）。rmean与RCmax、RCc均呈显著负相关。rmean与AL无统计学意义相关，R与AL、RCmax、RCc呈显著负相关。rmean与r呈显著正相关，RCmax与AL呈显著负相关，与RCc呈显著正相关。结论：视网膜“甜甜圈”区的视网膜形态可能在很大程度上与眼睛的内在形态发育有关。具体而言，小眼睛的RCc和RCmax值较大，rmean值较小，而大眼睛的RCc和RCmax值则相反。然而，AL可能与该区域的局部形态变化有关，主要体现在RCmax区域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.