The electroretinogram as a means to study the physiology of the retina.

Q2 Medicine

Handbook of clinical neurology Pub Date : 2026-01-01 DOI:10.1016/B978-0-443-22212-2.00012-4

Jan Kremers, Cord Huchzermeyer, Anneka Joachimsthaler

引用次数: 0

Abstract

The electroretinogram (ERG) is an important assay for retinal physiology. This noninvasive recording can be used for basic and disease-related research. This chapter addresses ERGs, recorded in humans and nonhuman primates, for assessing retinal physiology and for clinical application. We will also describe ERG recordings in mice that are often used for studying basic retinal processes and for preclinical research. The basics of ERG recording techniques and experimental procedures will be discussed. A brief description of the standard full-field stimuli and their corresponding ERG responses is given, with indications on the cellular origin of the different response components. The chapter also describes new developments in ERG stimulus techniques that are potentially interesting for expanding the use of ERGs in basic and clinical research.

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视网膜电图是研究视网膜生理学的一种手段。

视网膜电图（ERG）是一项重要的视网膜生理检查。这种无创记录可用于基础研究和疾病相关研究。本章讨论了记录在人类和非人类灵长类动物中的eeg，用于评估视网膜生理学和临床应用。我们还将描述经常用于研究基本视网膜过程和临床前研究的小鼠的ERG记录。将讨论ERG记录技术的基础和实验程序。简要描述了标准的全场刺激及其相应的ERG反应，并指出了不同反应成分的细胞起源。本章还描述了电刺激技术的新发展，这些技术对于扩大电刺激在基础和临床研究中的应用可能很有趣。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Handbook of clinical neurology Medicine-Neurology (clinical)

CiteScore

4.10

自引率

0.00%

发文量

302

期刊介绍： The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.