Cerebral Infarction Diagnosed as Isolated Cardiac Sarcoidosis.

NMC case report journal Pub Date : 2026-04-27 eCollection Date: 2026-01-01 DOI:10.2176/jns-nmc.2025-0255
Yasutaka Adachi, Riku Mihara, Taiji Okada, Minoru Ideguchi, Kenta Koketsu, Nobuaki Kobayashi, Kyongsong Kim, Yasuo Murai
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Abstract

Cardiac sarcoidosis elicits cardiac disorders due to granuloma formation in cardiac tissue; it can lead to cerebral infarcts. We encountered a 72-year-old Japanese male with isolated cardiac sarcoidosis diagnosed after a cardiogenic cerebral infarction. He suffered a sudden-onset disturbance of consciousness, aphasia, and right hemiparesis. His National Institutes of Health Stroke Scale score was 17. The diagnosis was left middle cerebral artery occlusion due to cardiogenic embolism. Percutaneous thrombectomy achieved thrombolysis and recanalization of the cerebral infarction; his National Institutes of Health Stroke Scale score improved to 0. Cardiac ultrasonography revealed an enlarged left atrial diameter, a thinned inferior ventricular wall, a ventricular aneurysm, and left ventricular systolic dysfunction. During the clinical course, ventricular tachycardia was noted; sarcoidosis was suspected as the underlying disease. As no definitive diagnosis could be made, he was discharged on the 54th day of hospitalization. 18F-fluorodeoxyglucose positron emission tomography in the outpatient department showed localized abnormal accumulation in the left ventricle, and he was diagnosed with isolated cardiac sarcoidosis. Steroid treatment was added to anticoagulation therapy. There have been no recurrent cerebral infarctions or lesions in other organs. Cardiac sarcoidosis can be 1 cause of cardiogenic cerebral infarction.

脑梗死诊断为孤立性心脏结节病。
心脏结节病由于心脏组织中形成肉芽肿而引起心脏疾病;它会导致脑梗塞。我们遇到了一位72岁的日本男性,他在心源性脑梗死后被诊断为孤立的心脏结节病。他突然出现意识障碍、失语和右半瘫。他的美国国立卫生研究院中风量表得分为17分。诊断为心源性栓塞引起的左大脑中动脉闭塞。经皮取栓实现脑梗死溶栓再通;他的美国国立卫生研究院中风量表得分提高到0分。心脏超声检查显示左心房直径增大,下心室壁变薄,心室动脉瘤,左心室收缩功能不全。在临床过程中,注意到室性心动过速;怀疑结节病为基础疾病。由于无法确诊,他于住院第54天出院。门诊18f -氟氧葡萄糖正电子发射断层扫描显示左心室局部异常积聚,诊断为孤立性心脏结节病。抗凝治疗中加入类固醇治疗。没有复发性脑梗死或其他器官病变。心脏结节病是心源性脑梗死的一种病因。
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