Convergent and Predictive Validity of the 1-Minute Sit-to-Stand Test in Patients With Acute Decompensated Heart Failure

IF 4 2区医学 Q1 REHABILITATION

Archives of physical medicine and rehabilitation Pub Date : 2026-10-01 Epub Date: 2026-05-23 DOI:10.1016/j.apmr.2026.05.009

Xiu Zhang MSc, Zeruxin Luo MSc, Ting Liu MD, Yu Kang MD, Mengxuan Yang MSc, Yuqiang Wang PhD, Martijn A. Spruit PhD, Pengming Yu PhD, Qing Zhang MD

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引用次数: 0

Abstract

Objectives

To evaluate the convergent validity and prognostic validity of the 1-minute sit-to-stand test (1-min STST) as a practical functional assessment tool in patients hospitalized with acute decompensated heart failure (ADHF) during the early postdischarge period.

Design

Prospective cohort study

Setting

West China Hospital of Sichuan University.

Participants

A total of 153 patients hospitalized with ADHF.

Interventions

At hospital discharge, participants underwent assessment with the 1-min STST, Short Physical Performance Battery (SPPB), and 6-minute walk test (6MWT). All patients were followed for 180 days after discharge.

Main Outcome Measures

The primary outcome was a 180-day composite endpoint of all-cause mortality or HF-related readmission. Pearson correlation was used to examine associations between 1-min STST repetitions, SPPB score, and 6-minute walk distance. Receiver operating characteristic analysis assessed their ability to predict 180-day composite events (rehospitalization or death), with optimal cutoffs from the Youden Index and area under the curve values (AUCs) compared by DeLong’s test. Receiver operating characteristic thresholds were used in Kaplan-Meier analyses (log-rank test), and Cox models estimated adjusted hazard ratios. Statistical significance was set at P≤.05.

Results

A total of 153 patients completed the 1-min STST, SPPB, and 6MWT, with mean values of 19.9 repetitions, 10.3 points, and 356.4 m, respectively. The 1-min STST demonstrated strong convergent validity with 6-minute walk distance (r=.727; P<.001). The 1-min STST showed good predictive performance for the 180-day composite endpoint (AUC=0.786), comparable to 6MWT (AUC=0.708). Patients achieving ≥16 repetitions had significantly higher cumulative survival and better functional capacity.

Conclusions

The 1-min STST is a field exercise test that strongly correlates with the 6MWT and provides prognostic insight in patients with ADHF. A threshold of ≥16 repetitions identifies patients with better survival/less hospitalizations, supporting its utility in clinical risk stratification.

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急性失代偿性心力衰竭患者1分钟坐立试验的收敛性和预测有效性

目的：评价1分钟坐立试验（1 min STST）作为急性失代偿性心力衰竭（ADHF）出院早期住院患者实用功能评估工具的收敛效度和预后效度。设计：前瞻性队列研究设置：四川大学华西医院。参与者：共153例ADHF住院患者。干预措施：出院时，参与者接受1分钟STST、短体能测试（SPPB）和6分钟步行测试（6MWT）的评估。出院后随访180 d。主要结局指标：主要结局是180天的全因再住院或死亡的综合终点。Pearson相关性检验了1分钟STST重复次数、SPPB评分和6MWD之间的关系。ROC分析评估了他们预测180天复合事件（再住院或死亡）的能力，通过DeLong检验比较了约登指数和auc的最佳截止点。Kaplan-Meier分析（log-rank检验）采用ROC阈值，Cox模型估计调整后的风险比。P≤0.05，差异有统计学意义。结果：153例患者完成了1 min STST、SPPB和6MWT，平均值分别为19.9次、10.3分和356.4米。1分钟STST与6MWT具有很强的聚合效度（r=0.727）。结论：1分钟STST是一种与6MWT密切相关的野外练习试验，可为ADHF患者提供预后信息。≥16次重复的阈值可识别生存率更高/住院次数更少的患者，支持其在临床风险分层中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of physical medicine and rehabilitation 医学-康复医学

CiteScore

6.20

自引率

4.70%

发文量

495

审稿时长

38 days

期刊介绍： The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities. Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.