Epidemiological Investigation of a Corrosive Chemical Leak from a Container Depot Affecting Students at Tughlakabad, Southeast District of Delhi, India
{"title":"Epidemiological Investigation of a Corrosive Chemical Leak from a Container Depot Affecting Students at Tughlakabad, Southeast District of Delhi, India","authors":"Sushma Choudhary*, , , Jayanti Singh, , , Anurag Sharma, , and , Meera Dhuria, ","doi":"10.1021/acs.chas.6c00030","DOIUrl":null,"url":null,"abstract":"<p ><b>Introduction:</b> A chemical leak of 2-chloro-5-chloromethylpyridine occurred at Tughlakabad Inland Container Depot (ICD) in the Southeast District of Delhi on May 6, 2017, affecting over 600 individuals. The National Centre for Disease Control of India investigated the incident. <b>Methods:</b> The study defined “a case” as “eye irritation or breathlessness in a resident or student of the Tughlakabad ward on May 6”. The investigation team reviewed hospital records and surveyed schools and neighborhoods adjacent to the ICD. Key informants were interviewed, followed by a 1:2 unmatched case-control study. <b>Results:</b> There were 619 cases (92% female) with no deaths; the median age was 13 years. The most common symptom experienced was eye irritation (99%). Univariate analysis of the case-control study showed that walking through the ICD exit track was the single main factor associated with the illness (OR = 5.4 [95% CI = 2.1–14.1], <i>P</i> < 0.001). The spill was reportedly covered with sand, but the removal of the mixture from the site was not carried out. No one, whether directly affected or not, had received any communication about the spill in the area. <b>Conclusions:</b> This chemical spill caused illnesses among individuals who had trespassed on the ICD exit road. Inappropriate chemical spill management and poor risk communication likely exacerbated the illnesses. The study recommends proper implementation of chemical neutralization and risk communication protocols.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"33 3","pages":"539–544"},"PeriodicalIF":3.4000,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acs.chas.6c00030","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chemical health & safety","FirstCategoryId":"1085","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acs.chas.6c00030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/5/2 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Introduction: A chemical leak of 2-chloro-5-chloromethylpyridine occurred at Tughlakabad Inland Container Depot (ICD) in the Southeast District of Delhi on May 6, 2017, affecting over 600 individuals. The National Centre for Disease Control of India investigated the incident. Methods: The study defined “a case” as “eye irritation or breathlessness in a resident or student of the Tughlakabad ward on May 6”. The investigation team reviewed hospital records and surveyed schools and neighborhoods adjacent to the ICD. Key informants were interviewed, followed by a 1:2 unmatched case-control study. Results: There were 619 cases (92% female) with no deaths; the median age was 13 years. The most common symptom experienced was eye irritation (99%). Univariate analysis of the case-control study showed that walking through the ICD exit track was the single main factor associated with the illness (OR = 5.4 [95% CI = 2.1–14.1], P < 0.001). The spill was reportedly covered with sand, but the removal of the mixture from the site was not carried out. No one, whether directly affected or not, had received any communication about the spill in the area. Conclusions: This chemical spill caused illnesses among individuals who had trespassed on the ICD exit road. Inappropriate chemical spill management and poor risk communication likely exacerbated the illnesses. The study recommends proper implementation of chemical neutralization and risk communication protocols.
2017年5月6日,德里东南部的图格拉卡巴德内陆集装箱仓库(ICD)发生了2-氯-5-氯甲基吡啶化学泄漏,影响了600多人。印度国家疾病控制中心对该事件进行了调查。方法:研究将“病例”定义为“5月6日Tughlakabad病房的住院医生或学生出现眼睛刺激或呼吸困难”。调查小组审查了医院记录,并调查了ICD附近的学校和社区。对关键举报人进行访谈,然后进行1:2的病例对照研究。结果:619例,其中女性92%,无死亡病例;平均年龄为13岁。最常见的症状是眼睛刺激(99%)。病例对照研究的单因素分析显示,通过ICD出口通道行走是与疾病相关的单一主要因素(OR = 5.4 [95% CI = 2.1-14.1], P < 0.001)。据报道,泄漏物被沙子覆盖,但没有将混合物从现场清除。无论是否受到直接影响,没有人收到有关该地区漏油的任何通知。结论:该化学品泄漏导致了侵入ICD出口道路的个体患病。不当的化学品泄漏管理和不良的风险沟通可能加剧了这些疾病。该研究建议适当实施化学中和和风险通报协议。