Probable sexual transmission of dengue virus serotype 1 from a male traveler to his female partner: A case report.

IF 4.6 2区医学 Q1 INFECTIOUS DISEASES

International Journal of Infectious Diseases Pub Date : 2026-09-01 Epub Date: 2026-05-22 DOI:10.1016/j.ijid.2026.108807

Jingjing Yang, Jinshen Wang, Jieru Pan, Shuai Zhang, Desi Zheng, En Lin, Jinzhang Wang, Shenggen Wu, Xiaoyang Zhang

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引用次数: 0

Abstract

Background: Dengue is primarily transmitted by Aedes mosquitoes, whereas sexual transmission has rarely been reported. We describe a probable case of male-to-female sexual transmission of dengue virus serotype 1 (DENV-1) in southeastern China.

Case presentation: A 41-year-old woman developed fever and myalgia on March 11, 2026, and tested positive for DENV-1 RNA and NS1 antigen, with negative anti-DENV IgM and IgG, consistent with early acute infection. Her husband had developed dengue in Timor-Leste on February 18, returned to China on March 4, and had unprotected sexual intercourse with her on March 5-7. At investigation, DENV RNA was undetectable in his blood but remained detectable in semen. Local vector-borne transmission appeared less likely because no substantial dengue activity was identified, the Breteau Index was 2, no adult Aedes mosquitoes were captured, and mean daily temperatures during the relevant period were low.

Conclusion: Taken together, the epidemiologic timeline, laboratory findings, and limited support for local mosquito-borne transmission were most consistent with probable sexual transmission of DENV-1.

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登革病毒血清型1可能由男性旅行者性传播给其女性伴侣：一个病例报告。

背景：登革热主要由伊蚊传播，而性传播很少有报道。我们报告了一例中国东南部登革热病毒血清型1 （DENV-1）可能的男性-女性性传播病例。病例介绍：一名41岁女性于2026年3月11日出现发热和肌痛，DENV-1 RNA和NS1抗原检测呈阳性，抗denv IgM和IgG阴性，符合早期急性感染。她的丈夫于2月18日在东帝汶患上登革热，3月4日返回中国，并于3月5日至7日与她发生无保护性交。在调查中，DENV RNA在其血液中检测不到，但在精液中仍可检测到。由于未发现大量登革热活动，布雷图指数为2，未捕获成伊蚊，且相关期间的日平均气温较低，因此本地媒介传播的可能性较低。结论：综合来看，流行病学时间线、实验室发现和对当地蚊媒传播的有限支持与DENV-1可能的性传播最为一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Infectious Diseases 医学-传染病学

CiteScore

18.90

自引率

2.40%

发文量

1020

审稿时长

30 days

期刊介绍： International Journal of Infectious Diseases (IJID) Publisher: International Society for Infectious Diseases Publication Frequency: Monthly Type: Peer-reviewed, Open Access Scope: Publishes original clinical and laboratory-based research. Reports clinical trials, reviews, and some case reports. Focuses on epidemiology, clinical diagnosis, treatment, and control of infectious diseases. Emphasizes diseases common in under-resourced countries.