Hot and Cold: Malignant Hyperthermia Without Fever in a Burn Patient.

IF 1.9 4区 医学 Q3 CRITICAL CARE MEDICINE
Chloe K Nobuhara, Pooja Yesantharao, Jesse Tai, Deepak Gupta, Scott Ahlbrand, Clifford Sheckter
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引用次数: 0

Abstract

Malignant hyperthermia (MH) is a rare, lifethreatening condition typically characterized by a rapid increase in body temperature and muscle rigidity in response to anesthetics. However, patients with extensive burn injuries have impaired thermoregulation and intraoperative heat loss, which can mask this classic hyperthermic response. We present the case of a 38-year-old female with a 23% total body surface area flame burn who developed a severe MH crisis during tangential excision following exposure to sevoflurane. Despite profound hypercapnia, acidosis, hyperkalemia, and extremity rigidity, the patient remained entirely afebrile throughout the event. Prompt recognition of the crisis by the surgical and anesthesia teams, followed by immediate administration of dantrolene, led to a rapid reversal of her metabolic derangements and a successful recovery.

热与冷:烧伤患者无发热的恶性高热。
恶性高热症(MH)是一种罕见的危及生命的疾病,其典型特征是对麻醉剂的反应,体温和肌肉僵硬迅速升高。然而,大面积烧伤患者的体温调节和术中热损失受损,这可以掩盖这种典型的热反应。我们报告一例38岁女性,体表面积23%的火焰烧伤,暴露于七氟醚后切线切除时出现严重MH危象。尽管有严重的高碳酸血症、酸中毒、高钾血症和四肢僵硬,患者在整个事件中仍然完全不发烧。外科和麻醉小组迅速认识到这一危机,随后立即给药丹曲林,使她的代谢紊乱迅速逆转,并成功康复。
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来源期刊
CiteScore
2.60
自引率
21.40%
发文量
535
审稿时长
4-8 weeks
期刊介绍: Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.
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