{"title":"[Cerebral Malaria].","authors":"Kenji Ohnishi","doi":"10.11477/mf.188160960780050611","DOIUrl":null,"url":null,"abstract":"<p><p>When patients with malaria exhibit impaired consciousness, cerebral malaria should be considered. Although malaria parasites infect red blood cells, they do not infect neurons. Cerebral malaria is thought to occur when parasite-infected red blood cells adhere to endothelial cells lining the brain microvasculature, obstructing the vascular lumen; however, its detailed pathophysiology remains unclear. If cerebral malaria is suspected, intravenous artesunate should be initiated as soon as possible.</p>","PeriodicalId":52507,"journal":{"name":"Brain and Nerve","volume":"78 5","pages":"611-615"},"PeriodicalIF":0.0000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain and Nerve","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11477/mf.188160960780050611","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
When patients with malaria exhibit impaired consciousness, cerebral malaria should be considered. Although malaria parasites infect red blood cells, they do not infect neurons. Cerebral malaria is thought to occur when parasite-infected red blood cells adhere to endothelial cells lining the brain microvasculature, obstructing the vascular lumen; however, its detailed pathophysiology remains unclear. If cerebral malaria is suspected, intravenous artesunate should be initiated as soon as possible.
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