Rajajeyakumar Manivel, A S Vickram, Nidhi Sharma, Sargunadevi Sivanantham
{"title":"Revolutionary Approaches to Sperm Selection: Enhancing Male Fertility Through Advanced Processing Techniques.","authors":"Rajajeyakumar Manivel, A S Vickram, Nidhi Sharma, Sargunadevi Sivanantham","doi":"10.1007/s13224-025-02136-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Male infertility, often worsened by oxidative stress, remains a challenging issue that significantly impacts sperm quality.</p><p><strong>Objectives: </strong>Reactive oxygen species (ROS) are key contributors to sperm DNA damage, reduced motility, and abnormal morphology. In response to these challenges, advanced sperm processing techniques like density gradient centrifugation and magnetic-activated sperm cell sorting have been developed to optimize sperm selection and reduce ROS levels.</p><p><strong>Conclusion: </strong>This commentary examines recent research on these techniques and their impact on sperm quality, highlighting their potential in the treatment of male infertility.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"176-178"},"PeriodicalIF":0.5000,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172079/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Obstetrics and Gynecology of India","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s13224-025-02136-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/2 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Male infertility, often worsened by oxidative stress, remains a challenging issue that significantly impacts sperm quality.
Objectives: Reactive oxygen species (ROS) are key contributors to sperm DNA damage, reduced motility, and abnormal morphology. In response to these challenges, advanced sperm processing techniques like density gradient centrifugation and magnetic-activated sperm cell sorting have been developed to optimize sperm selection and reduce ROS levels.
Conclusion: This commentary examines recent research on these techniques and their impact on sperm quality, highlighting their potential in the treatment of male infertility.
期刊介绍:
Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: · Original Article· Case Report · Instrumentation and Techniques · Short Commentary · Correspondence (Letter to the Editor) · Pictorial Essay