Correlation of Applebaum Uterine Scoring System with Pregnancy Outcomes among Infertile Patients Undergoing Embryo Transfer in a Tertiary Care Hospital.

Abstract

Introduction: Embryo transfer is the most crucial and final step in IVF cycle, accounting for about 30% failures in case of improper technique. Therefore, a new concept of evaluating uterine receptivity by M. Applebaum was developed that has shown promising results to predict IVF outcome.

Aim and objectives: To evaluate uterine receptivity by using Applebaum scoring system and correlate the parameters with pregnancy outcomes among infertile patients undergoing embryo transfer in a tertiary care hospital in North India.

Material and methods: This was a prospective interventional study, conducted in Department of Obstetrics and Gynecology at SRMSIMS, Bareilly on 60 patients who presented with infertility during the period from July 2023 to September 2023. To assess uterine receptivity, ultrasonographic and Doppler parameters were analyzed and scored as per parameters of Applebaum uterine scoring system and serum beta-human chorionic gonadotropin was performed 14 days after ET to confirm the pregnancy.

Observations: The mean age and BMI among the females who conceived was 34.78 ± 6.28 years and 23.7 ± 2.17 kg/m2respectively, majority of whom had marriage duration of 4-6 years. Pulsatility Index, myometrial contraction, and total Applebaum uterine score parameters were significantly (p 0.05) higher among patients with pregnancy than without pregnancy.

Conclusion: The endometrial receptivity is predeterminant in predicting the pregnancy outcome. Uterine scoring system will help to perform embryo transfers in only favourable uterine environment.