Concurrent Bladder Urothelial Carcinoma and Prostate Tuberculosis: A Case Report.

Abstract

Introduction: Tuberculosis is associated with an increased risk of bladder cancer; however, the simultaneous occurrence of urogenital tuberculosis and bladder cancer is rare. Primary prostate tuberculosis is relatively uncommon in patients with urogenital tuberculosis.

Case presentation: A 68-year-old man presented with gross hematuria and irritative voiding symptoms. Cystoscopy revealed a bladder tumor. The PSA level was elevated (8.32 ng/mL), and MRI findings suggested prostate cancer. Chest radiography and CT indicated pulmonary tuberculosis, which was confirmed by sputum mycobacterial culture and PCR. Urine mycobacterial cultures revealed urinary tuberculosis. TURBT and prostate biopsy were performed after initiating treatment for tuberculosis and confirming sputum conversion. Histopathological examination revealed urothelial carcinoma of the bladder and prostate tuberculosis.

Conclusion: This is the first reported case of concurrent bladder urothelial carcinoma and prostate tuberculosis. Patients with pulmonary tuberculosis may benefit from evaluation for urogenital tuberculosis, including prostatic involvement, and consideration of coexisting urothelial carcinoma.