Gastric Cancer Prevention Efforts in Sub-Saharan Africa: An Example of Zambia and Nigeria.

IF 4.6 2区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Helicobacter Pub Date : 2026-05-01 DOI:10.1111/hel.70108

Violet Kayamba, Stella Smith

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引用次数: 0

Abstract

Introduction: Without any intervention, a more than six-fold increase in gastric cancer cases is expected in sub-Saharan Africa (SSA) among people born between 2008 and 2017. Therefore, initiatives aimed at curbing this projected increase are urgently required. In this review, we highlight the efforts made in two SSA countries, Zambia and Nigeria.

Methodology: A thorough review of the published literature on gastric cancer in both countries was conducted. We did not employ any time limits, and all information sources were consistent with our predetermined objectives. Articles in English were obtained from Google Scholar, Scopus, PubMed, and AJOL. We also conducted an in-depth analysis of the gastric cancer risk factors reported in Zambia.

Results: Zambia and Nigeria lack active population-based gastric cancer prevention programs. However, concerted efforts are being made to understand the occurrence of gastric cancer and its major risk factor, Helicobacter pylori (H. pylori) infection. As in other countries, H. pylori resistance to commonly used antibiotics affects the success rate of eradication therapy. Initiatives are underway to collect robust data and design optimal therapies for H. pylori eradication that are suitable for the SSA population.

Conclusion: Zambia and Nigeria have recently made significant strides in collating information on gastric cancer and its risk factors. This is despite the many prevailing challenges, compounded by resource limitations.

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撒哈拉以南非洲的胃癌预防工作：以赞比亚和尼日利亚为例。

在没有任何干预的情况下，预计撒哈拉以南非洲（SSA） 2008年至2017年出生的人群中胃癌病例将增加6倍以上。因此，迫切需要采取旨在遏制这一预期增长的主动行动。在本次审查中，我们重点介绍了赞比亚和尼日利亚这两个SSA国家所做的努力。方法：对两国发表的关于胃癌的文献进行了全面的回顾。我们没有设定任何时间限制，所有信息来源都符合我们预定的目标。英文文章来源于谷歌Scholar、Scopus、PubMed和AJOL。我们还对赞比亚报道的胃癌危险因素进行了深入分析。结果：赞比亚和尼日利亚缺乏积极的以人群为基础的胃癌预防项目。然而，人们正在共同努力了解胃癌的发生及其主要危险因素幽门螺杆菌（h.p ylori）感染。与其他国家一样，幽门螺杆菌对常用抗生素的耐药性影响根除治疗的成功率。目前正在采取措施收集可靠的数据，并设计适合SSA人群的幽门螺杆菌根除的最佳疗法。结论：赞比亚和尼日利亚最近在整理胃癌及其危险因素的信息方面取得了重大进展。尽管目前存在许多挑战，加上资源有限，情况更加复杂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Helicobacter 医学-微生物学

CiteScore

8.40

自引率

9.10%

发文量

审稿时长

2 months

期刊介绍： Helicobacter is edited by Professor David Y Graham. The editorial and peer review process is an independent process. Whenever there is a conflict of interest, the editor and editorial board will declare their interests and affiliations. Helicobacter recognises the critical role that has been established for Helicobacter pylori in peptic ulcer, gastric adenocarcinoma, and primary gastric lymphoma. As new helicobacter species are now regularly being discovered, Helicobacter covers the entire range of helicobacter research, increasing communication among the fields of gastroenterology; microbiology; vaccine development; laboratory animal science.