Retrograde Ureteric Stent Placement Versus Percutaneous Nephrostomy for Infected Ureteral Obstruction in Diabetic Patients: A Retrospective Study.

IF 0.9 4区医学 Q4 UROLOGY & NEPHROLOGY

Archivos Espanoles De Urologia Pub Date : 2026-04-01 DOI:10.56434/j.arch.esp.urol.20267903.53

Bin Su, Kang Chen, Pin Wu, Kangyu Li, Yansi Lan

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引用次数: 0

Abstract

Objective: To compare the effectiveness and safety of retrograde ureteral stent (RUS) and percutaneous nephrostomy (PCN) in the treatment of diabetic patients with infected ureteral obstruction.

Methods: From February 2022 to February 2024, 202 diabetic patients with infected ureteral obstruction were included. Data were obtained retrospectively and the outcomes including complications, period for return to serum creatinine nadir, white blood cell (WBC) count and blood urea nitrogen were measured. Logistic regression was used to explore risk factors for postoperative complications.

Results: A total of 202 patients (PCN group: 102 patients; RUS group: 100 patients) were included in the final analysis. The incidence of complications of Clavien-Dindo Grade ≥ II was significantly higher in the PCN group (34.3%) than in the RUS group (11.0%, p < 0.001). The RUS group showed better renal function preservation rate (87.0% vs. 73.5%, p = 0.016) and lower recurrent urinary tract infection rate (11.0% vs. 21.6%, p = 0.042). After adjusting for potential confounding factors, the RUS group had a significantly lower risk of postoperative complications compared with the PCN group. In addition, the duration of diabetes mellitus, the amplitude of postoperative blood glucose fluctuation, and the duration of insulin use were independent risk factors for postoperative complications (p < 0.05).

Conclusions: RUS appears to be superior to PCN in reducing postoperative complications, preserving renal function, and lowering infection recurrence in diabetic patients with infected ureteral obstruction.

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逆行输尿管支架置入与经皮肾造瘘治疗糖尿病患者感染输尿管梗阻的回顾性研究

目的：比较逆行输尿管支架（RUS）与经皮肾造口术（PCN）治疗糖尿病合并感染性输尿管梗阻的有效性和安全性。方法：选取2022年2月~ 2024年2月合并感染性输尿管梗阻的糖尿病患者202例。回顾性收集资料，测定并发症、血清肌酐降至最低点的时间、白细胞计数和尿素氮。采用Logistic回归分析术后并发症的危险因素。结果：共纳入202例患者，其中PCN组102例，RUS组100例。Clavien-Dindo分级≥II的并发症发生率PCN组（34.3%）明显高于RUS组（11.0%,p < 0.001）。RUS组肾功能保存率（87.0%比73.5%,p = 0.016）较好，尿路感染复发率（11.0%比21.6%,p = 0.042）较低。在调整了潜在的混杂因素后，RUS组与PCN组相比，术后并发症的风险显著降低。糖尿病病程、术后血糖波动幅度、胰岛素使用时间是术后并发症的独立危险因素（p < 0.05）。结论：在糖尿病合并感染性输尿管梗阻患者中，RUS在减少术后并发症、保留肾功能、降低感染复发方面优于PCN。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archivos Espanoles De Urologia UROLOGY & NEPHROLOGY-

CiteScore

0.90

自引率

0.00%

发文量

111

期刊介绍： Archivos Españoles de Urología published since 1944, is an international peer review, susbscription Journal on Urology with original and review articles on different subjets in Urology: oncology, endourology, laparoscopic, andrology, lithiasis, pediatrics , urodynamics,... Case Report are also admitted.