Endometrial osseous metaplasia presenting as a suspected intrauterine device: diagnostic pitfalls and hysteroscopic management—case report

AJOG global reports Pub Date : 2026-05-01 Epub Date: 2026-04-12 DOI:10.1016/j.xagr.2026.100643
Fabio Noriel Rojas Rojas MD , Víctor S. Rangel MD
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Abstract

Endometrial osseous metaplasia is a rare cause of abnormal uterine bleeding that can mimic an intrauterine foreign body on imaging, leading to diagnostic uncertainty. We report a 48-year-old woman with long-standing abnormal uterine bleeding, prior term vaginal deliveries, and no history of uterine instrumentation or pregnancy loss. Transvaginal ultrasound suggested an intrauterine device. Diagnostic hysteroscopy revealed a firm, whitish, cylindrical lesion with multiple projections anchored at the isthmus and tightly adherent to the myometrium, precluding complete removal due to perforation risk. Representative biopsies were obtained with minimal bleeding. Histopathology confirmed mature bone consistent with endometrial osseous metaplasia, without malignancy or foreign material. The patient experienced symptomatic improvement post-procedure and had an uncomplicated outpatient follow-up. A brief review of the literature indicates that although most cases are linked to prior obstetric events or uterine instrumentation, osseous metaplasia can occur in their absence and may present as an apparent intrauterine device on ultrasound. This report underscores the importance of considering osseous metaplasia in the differential diagnosis of abnormal uterine bleeding and highlights hysteroscopy as the definitive diagnostic and therapeutic approach to obtain targeted tissue and guide management while avoiding unnecessary interventions.
子宫内膜骨化生表现为疑似宫内节育器:诊断缺陷和宫腔镜处理病例报告
子宫内膜骨性化生是一种罕见的异常子宫出血的原因,在影像学上可以模仿宫内异物,导致诊断不确定。我们报告一个48岁的妇女长期异常子宫出血,以前阴道分娩足月,并没有子宫内固定或妊娠丢失的历史。经阴道超声显示有宫内节育器。诊断性宫腔镜检查显示一个坚固的、白色的圆柱形病变,有多个突起,锚定在峡部,紧紧附着在肌层上,由于有穿孔的风险,不能完全切除。在少量出血的情况下进行了有代表性的活检。组织病理学证实成熟骨符合子宫内膜骨化生,无恶性肿瘤或异物。患者在手术后症状得到改善,并进行了简单的门诊随访。对文献的简要回顾表明,尽管大多数病例与先前的产科事件或子宫内固定有关,但骨化生可以在没有这些事件的情况下发生,并且可能在超声上表现为明显的宫内节育器。本报告强调了在异常子宫出血鉴别诊断中考虑骨性化生的重要性,并强调宫腔镜作为明确的诊断和治疗方法,以获得有针对性的组织和指导管理,同时避免不必要的干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
AJOG global reports
AJOG global reports Endocrinology, Diabetes and Metabolism, Obstetrics, Gynecology and Women's Health, Perinatology, Pediatrics and Child Health, Urology
CiteScore
1.20
自引率
0.00%
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0
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