Analysis of a Standardized Approach to Healthcare Worker Hazardous Medication Surveillance: Lessons learned and future enhancements.

IF 1.4

Journal of occupational and environmental medicine Pub Date : 2026-05-05 DOI:10.1097/JOM.0000000000003743

Laura Breeher, Richard Newcomb, Kristine Hanson, Caitlin Hainy, LuAnn Fowler, Kelsey Hoyer, Alzhraa Abbas, Krista Severson, Melanie Swift

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引用次数: 0

Abstract

Objective: To evaluate the effectiveness of a standardized hazardous medication surveillance program and identify occupational factors associated with adverse health outcomes among healthcare workers (HCWs).

Methods: We analyzed data from 2,625 HCWs enrolled in a multi-site surveillance program (2020-2022). Participants completed a standardized questionnaire and underwent complete blood count testing. Exposure was categorized by weekly time handling hazardous medications. Associations were evaluated using univariate and multivariable analyses.

Results: Higher exposure (>8 hours/week) was associated with increased symptom reporting, hazardous medication spills, and adverse reproductive outcomes. Female sex, older age, and spill exposure independently predicted symptom reporting and reproductive outcomes. No significant association was observed between exposure intensity and abnormal blood counts.

Conclusion: Questionnaire-based surveillance effectively identified exposure-related health risks, whereas routine complete blood count testing showed limited utility.

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卫生保健工作者危险药物监测的标准化方法分析：经验教训和未来的改进。

目的：评价标准化危险药物监测项目的有效性，并确定与卫生保健工作者（HCWs）不良健康结果相关的职业因素。方法：我们分析了参加2020-2022年多地点监测项目的2625名医护人员的数据。参与者完成了一份标准化问卷，并进行了全血细胞计数测试。暴露程度按每周处理危险药物的时间分类。使用单变量和多变量分析评估相关性。结果：较高的暴露（bbb8小时/周）与症状报告增加、危险药物泄漏和不良生殖结果相关。女性性别、年龄和泄漏暴露独立预测症状报告和生殖结果。暴露强度和血液计数异常之间没有明显的联系。结论：基于问卷的监测有效地识别了暴露相关的健康风险，而常规全血细胞计数检测的效用有限。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of occupational and environmental medicine

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