German Hypothermia Registry Improves Clinician Confidence and Harmonises Decentralised Neonatal Hypoxic-Ischaemic Encephalopathy Care in Germany.

IF 2.1 4区医学 Q1 PEDIATRICS

Acta Paediatrica Pub Date : 2026-05-08 DOI:10.1111/apa.70579

Till Dresbach, Khaled Abdelrahman, Sebiha Demir, Anne Groteklaes, Alexandra Boeckenhoff, Andreas Mueller, Hemmen Sabir

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引用次数: 0

Abstract

Aim: Decentralised implementation of therapeutic hypothermia (TH) for neonatal hypoxic-ischaemic encephalopathy (HIE) in Germany historically caused heterogeneous clinical practices. The aim of this study was to assess the impact of the German Hypothermia Registry on clinical standardisation and confidence in neonatal HIE care since its initiation in 2022.

Methods: We conducted a nationwide, two-phase, web-based survey in 2022 (n = 66) and 2025 (n = 222). A longitudinal subgroup analysis included physicians participating in both surveys (n = 30). Outcomes included guideline adherence, subjective diagnostic and therapeutic confidence, and perceived needs for further standardisation.

Results: From 2022 to 2025, clinician confidence improved across most domains. Complete confidence in diagnosing HIE increased from 42.4% to 80.0% in the longitudinal subgroup, while confidence in performing TH rose from 53.0% to 86.7%. Clarity regarding inclusion criteria reached 100% among longitudinal participants. In contrast, complete confidence in neurological assessment (36.7%) and amplitude-integrated electroencephalography (aEEG) interpretation (60.0%) remained comparatively lower in 2025.

Conclusion: The German Hypothermia Registry markedly improved standardisation and clinician confidence in neonatal HIE care. However, neurological assessment and aEEG interpretation remain key areas requiring targeted educational support.

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德国低温登记提高临床医生的信心和协调分散的新生儿缺氧缺血性脑病护理在德国。

目的：在德国，新生儿缺氧缺血性脑病（HIE）的治疗性低温（TH）的分散性实施历来导致了不同的临床实践。本研究的目的是评估德国低温登记自2022年启动以来对新生儿HIE护理临床标准化和信心的影响。方法：我们于2022年（n = 66）和2025年（n = 222）在全国范围内进行了两期网络调查。纵向亚组分析包括参与两项调查的医生（n = 30）。结果包括指南依从性，主观诊断和治疗信心，以及对进一步标准化的感知需求。结果：从2022年到2025年，临床医生的信心在大多数领域都有所提高。纵向亚组诊断HIE的完全置信度从42.4%上升到80.0%，执行TH的置信度从53.0%上升到86.7%。在纵向参与者中，纳入标准的清晰度达到100%。相比之下，2025年神经学评估的完全置信度（36.7%）和振幅综合脑电图（aEEG）解释的完全置信度（60.0%）仍然相对较低。结论：德国低温登记显著提高了新生儿HIE护理的标准化和临床医生的信心。然而，神经评估和aEEG解释仍然是需要有针对性的教育支持的关键领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Paediatrica 医学-小儿科

CiteScore

6.50

自引率

5.30%

发文量

384

审稿时长

2-4 weeks

期刊介绍： Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries