The effectiveness and cost-effectiveness of cash plus interventions to prevent acute malnutrition in Somalia: evidence from an adaptive cluster randomised control trial.

IF 4.3 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Nadia Akseer, Kemish Kenneth Alier, Samantha Grounds, Sydney Garretson, Sagal Mohamud, Qundeel Khattak, Marina Tripaldi, Fabrizio Loddo, Said Aden Mohamoud, Adan Yusuf Mahdi, Mohamoud Ali Nur, Sadiq Mohamed Abdiqadir, Emily Mitchell, Andreas Kees, Mohamed Billow Mahat, Maimun Gure, Dahir Isaq Jibril, Dahir Gedi, Michael Ocircan P'Rajom, Meftuh Omer, Abdullahi Farah, Mohamed Abdirashid Osman, Abdiaziz Mohamed Adan, Farhan Mohamed Mohamoud, Abdullahi Muse Mohamoud, Abdifatah Ahmed Mohamed, Abdulkadir Ali Abdi, Adam Abdulkadir, Shelley Walton
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引用次数: 0

Abstract

Background: Acute malnutrition affects millions of children aged <5 years, as well as pregnant and lactating women globally, especially in humanitarian settings. Although cash plus interventions - cash or food transfers combined with complementary components - are widely implemented, evidence remains limited on which combinations and durations are most effective at preventing acute malnutrition.

Methods: We conducted a three-arm cluster-randomised trial within the 'Save the Children's Cash Plus for Nutrition' programme in Somalia. Monthly support was provided as cash alone (arm 1), cash plus social and behaviour change communication (arm 2), or cash plus an additional cash top-up (arm 3). Further, we randomised 33 villages across arms, targeting approximately 1500 households. Primary outcomes included the prevalence and incidence of acute malnutrition in children aged 6-59 months and in mothers, assessed at baseline, midline (three months), and endline (six months). We also conducted market monitoring, qualitative data collection, and analysis.

Results: Child acute malnutrition prevalence was approximately 15.0% in each arm at baseline. After three months, prevalence declined by 2.0 percentage points in arm 1 to 13.0% (95% confidence interval (CI) = 10.3, 16.1), representing a relative reduction of 13.3%. In arm 2, prevalence declined by 5.9 percentage points to 9.1% (95% CI = 6.8, 11.8), a relative reduction of 39.3%. In contrast, prevalence in arm 3 remained essentially unchanged, increasing to 15.1% (95% CI = 12.1, 18.6). By endline, there was little change from midline in all arms. Maternal malnutrition improved most in arm 2, but differences were not statistically significant. All arms showed improvements in dietary diversity and food security, but only arm 2 achieved sustained nutrition gains. Household livelihood conditions appeared to improve overall, though monthly expenditures nearly doubled. Arm 2 was the most effective and cost-effective.

Conclusions: Adding social and behaviour change communication to cash transfers significantly improved child nutrition compared to cash alone, highlighting that integrated approaches can enhance nutritional outcomes and at minimal additional cost in humanitarian settings.

Registration: ClinicalTrials.gov: NCT06642012.

现金加干预措施预防索马里急性营养不良的有效性和成本效益:来自适应性聚类随机对照试验的证据。
背景:急性营养不良影响着数百万的老年儿童。方法:我们在索马里的“拯救儿童现金+营养”项目中进行了一项三组随机试验。每月提供的支持包括单独的现金(第1组),现金加社会和行为改变沟通(第2组),或现金加额外的现金充值(第3组)。此外,我们随机选取了33个村庄,涉及大约1500户家庭。主要结局包括6-59月龄儿童和母亲急性营养不良的患病率和发生率,分别在基线、中线(3个月)和终点(6个月)进行评估。我们还进行了市场监测、定性数据收集和分析。结果:两组儿童急性营养不良发生率基线时约为15.0%。3个月后,第1组的患病率下降了2.0个百分点至13.0%(95%置信区间(CI) = 10.3, 16.1),相对降低了13.3%。在第二组中,患病率下降了5.9个百分点至9.1% (95% CI = 6.8, 11.8),相对降低了39.3%。相比之下,第3组的患病率基本保持不变,增加到15.1% (95% CI = 12.1, 18.6)。到尾线,所有手臂的中线变化不大。第2组产妇营养不良改善最多,但差异无统计学意义。所有小组在饮食多样性和粮食安全方面都有所改善,但只有第二小组实现了持续的营养增长。家庭生活条件总体上有所改善,但每月支出几乎翻了一番。第2组是最有效和最经济的。结论:与单独使用现金相比,在现金转移支付中加入社会和行为改变沟通可以显著改善儿童营养状况,强调综合方法可以在人道主义环境中以最小的额外成本改善营养结果。注册:ClinicalTrials.gov: NCT06642012。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Global Health
Journal of Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -
CiteScore
6.10
自引率
2.80%
发文量
240
审稿时长
6 weeks
期刊介绍: Journal of Global Health is a peer-reviewed journal published by the Edinburgh University Global Health Society, a not-for-profit organization registered in the UK. We publish editorials, news, viewpoints, original research and review articles in two issues per year.
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