Impact of melatonin injection in improving ovarian function in aged female pigeon.

IF 2 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Research Communications Pub Date : 2026-05-07 DOI:10.1007/s11259-026-11260-x

Ying Wang, Haodong Zhang, Jing Chen, Dongzhi Miao, Xinyan Mao, Wanqing Li, Haiming Yang, Zhiyue Wang

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引用次数: 0

Abstract

Melatonin (MT) has been shown to extend laying period in aged hens, but its effects on aging pigeons remain unclear. 36 pairs of 5-year-old White King pigeons were assigned to either a treatment group receiving 1 mg of MT for five days or a control group given saline. The effect of MT injection on egg production in pigeon, assess histological characteristics of follicles, antioxidant parameters level and the related gene mRNA levels, steroid hormone levels and the expressions of synthesis genes on the fifth day of the laying interval. MT treatment significantly improved various aspects of egg quality. Moreover, MT increased follicle diameter and granulosa cell layer (GCL) thickness (P < 0.05). MT levels were elevated in plasma and hierarchy follicles yolks (P < 0.05). Progesterone concentrations rose in plasma (P < 0.05), however, estradiol levels decreased in plasma, F1 and F2 yolks (P < 0.05). MT also reduced ROS and MDA levels in plasma and F1 yolk (P < 0.05). Meanwhile, activities of SOD, TAC, and GSH-PX were significantly increased (P < 0.05). MT upregulated SOD1, CAT, and BCL2 mRNA levels in ovary and F1 GCL (P < 0.05). MT significantly increased ovarian expressions of HSD3B1 and CYP11A1, reducing HSD17B1 mRNA levels (P < 0.05); In F1 and F2 GCL, CYP11A1, CYP17A1, and CYP19A1 expressions were all elevated (P < 0.05). These findings suggest that MT promotes hierarchy follicle maturation, reduces apoptosis, thus extending egg-laying period in aging pigeons.

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褪黑素注射对老年雌鸽卵巢功能的影响。

褪黑素（MT）已被证明可以延长老年母鸡的产蛋期，但它对老年鸽子的影响尚不清楚。36对5岁的白王鸽子被分为两组，一组接受1毫克MT治疗，持续5天，另一组接受生理盐水治疗。研究MT注射液对产蛋鸽的影响，评估产蛋间隔第5天卵泡组织学特征、抗氧化参数水平及相关基因mRNA水平、类固醇激素水平和合成基因表达。MT处理显著提高了蛋品质的各个方面。此外，MT增加了卵泡直径和颗粒细胞层（GCL）厚度

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary Research Communications 农林科学-兽医学

CiteScore

2.50

自引率

0.00%

发文量

173

审稿时长

3 months

期刊介绍： Veterinary Research Communications publishes fully refereed research articles and topical reviews on all aspects of the veterinary sciences. Interdisciplinary articles are particularly encouraged, as are well argued reviews, even if they are somewhat controversial. The journal is an appropriate medium in which to publish new methods, newly described diseases and new pathological findings, as these are applied to animals. The material should be of international rather than local interest. As it deliberately seeks a wide coverage, Veterinary Research Communications provides its readers with a means of keeping abreast of current developments in the entire field of veterinary science.