Safety, Efficacy, and Quality of Life Outcomes of Bariatric and Metabolic Surgery in Korea: A Prospective Multicenter Cohort Study.

IF 3.1 3区医学 Q1 SURGERY

Obesity Surgery Pub Date : 2026-05-07 DOI:10.1007/s11695-026-08697-z

Sung Il Choi, Yoonseok Heo, Seung Wan Ryu, Sungsoo Park, Yeongkeun Kwon, Tae Kyung Ha, Yeon-Ji Lee, Sangjun Lee, Kyung Won Seo, Sang Hyun Kim, Ji Yeon Park, Jong-Han Kim

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引用次数: 0

Abstract

Introduction: This prospective multicenter cohort study aimed to assess the effectiveness and safety of bariatric and metabolic surgery (BMS) in Korean patients with class II obesity or higher and those with a body mass index (BMI) ≥ 27.5 kg/m².

Methods: Between September 2020 and December 2022, 116 patients undergoing BMS were enrolled from nine centers in Korea. Of these, 37 patients underwent gastric bypass and 79 underwent sleeve gastrectomy. Follow-up evaluations were performed for up to 2 years. Clinical data were collected alongside four quality of life (QOL) surveys (EQ-5D, IWQOL-lite, OP-scale, and BAROS) administered at 12, 24, 48, 72, and 96 weeks postoperatively. Clinical parameters included obesity severity, complications by surgery type, associated medical problems, nutritional status, and their longitudinal changes.

Results: The cohort had a mean age of 37.0 ± 11.1 years and a mean BMI of 41.9 ± 7.6 kg/m²; 71.6% of participants were female. Baseline associated medical problems included type 2 diabetes mellitus (T2DM) in 45 patients (38.8%), hypertension in 77 (66.4%), and hyperlipidemia in 77 (66.4%). Total weight loss reached 26.8% at 1 year, 27.5% at 1.5 years, and 24.7% at 2 years. Remission rates for T2DM, hypertension, and hyperlipidemia at 1 year were 80.7%, 50.0%, and 49.0%, respectively, increasing to 85.7%, 50.0%, and 71.4% at 2 years. No significant differences were observed between the procedures in postoperative weight trajectories, nutritional outcomes, or improvements of associated medical problem. All QOL scores showed significant and sustained improvement across all surveys. The overall complication rate was 12.1% (early: 0.9%, late: 11.2%), which was considered acceptable.

Conclusion: Gastric bypass and sleeve gastrectomy are effective and safe BMS procedures for Korean patients, providing substantial weight loss, remission of associated medical problems, and improved QOL.

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韩国减肥和代谢手术的安全性、有效性和生活质量：一项前瞻性多中心队列研究

本前瞻性多中心队列研究旨在评估韩国II级或以上肥胖患者以及体重指数(BMI)≥27.5 kg/m²的肥胖和代谢手术（BMS）的有效性和安全性。方法：在2020年9月至2022年12月期间，从韩国9个中心招募了116名接受BMS的患者。其中37例患者行胃旁路术，79例行袖式胃切除术。随访评估长达2年。收集临床数据，并在术后12、24、48、72和96周进行四项生活质量调查（EQ-5D、iwqol - life、OP-scale和BAROS）。临床参数包括肥胖严重程度、手术类型并发症、相关医疗问题、营养状况及其纵向变化。结果：该队列的平均年龄为37.0±11.1岁，平均BMI为41.9±7.6 kg/m²；71.6%的参与者为女性。基线相关医疗问题包括2型糖尿病（T2DM）患者45例（38.8%），高血压患者77例（66.4%），高脂血症患者77例（66.4%）。1年总体重减轻26.8%，1.5年减轻27.5%，2年减轻24.7%。T2DM、高血压和高脂血症的缓解率在1年时分别为80.7%、50.0%和49.0%，在2年时分别增加到85.7%、50.0%和71.4%。在术后体重轨迹、营养结果或相关医疗问题的改善方面，两种手术之间没有观察到显著差异。在所有调查中，所有生活质量得分都显示出显著和持续的改善。总并发症发生率为12.1%（早期：0.9%，晚期：11.2%），可接受。结论：对韩国患者来说，胃旁路和袖胃切除术是有效和安全的BMS手术，可显著减轻体重，缓解相关医疗问题，改善生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity Surgery 医学-外科

CiteScore

5.80

自引率

24.10%

发文量

567

审稿时长

3-6 weeks

期刊介绍： Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions. Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.