Timely administration of antibiotics for neonatal sepsis in the neonatal intensive care unit: A quality improvement initiative.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2026-05-04 DOI:10.1038/s41372-026-02710-0

Harjinder P Singh, Sheri Landazuri, Susan Wilkinson

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引用次数: 0

Abstract

Objective: To Improve timely administration of the first antibiotic dose in the neonatal intensive care unit (NICU) through a quality improvement (QI) initiative.

Study design: Conducted in a 53- bed NICU over 3 years involving 1094 neonates who received antibiotics for suspected sepsis. Using the Institute for Healthcare Improvement (IHI) methods, three interventions were made: NICU staff education; developed order sets for stat antibiotic doses and implementation of a secure code medication delivery system. Outcomes included the infants receiving their first antibiotic dose within 60 min of ordering and average time from order to administration.

Results: Infants receiving antibiotics within 60 min improved from baseline 32.7% to 84.4% over a 3 year period and has been sustained over 2 years. The average time to administration decreased from 93.3 min to 44.7 min.

Conclusion: A systematic multidisciplinary approach decreased the time from antibiotic order to administration time in the NICU.

查看原文本刊更多论文

在新生儿重症监护病房及时给予抗生素治疗新生儿败血症：一项质量改进倡议。

目的：通过质量改进（QI）倡议，提高新生儿重症监护病房（NICU）首次抗生素剂量的及时给药。研究设计：在一个53个床位的新生儿重症监护室进行，为期3年，涉及1094名因疑似败血症接受抗生素治疗的新生儿。采用卫生保健改善研究所（IHI）的方法，采取了三项干预措施：新生儿重症监护室工作人员教育；制定处方集，用于统计抗生素剂量，并实施安全代码给药系统。结果包括婴儿在下单后60分钟内接受第一次抗生素剂量和从下单到给药的平均时间。结果：在60分钟内接受抗生素治疗的婴儿在3年内从基线的32.7%提高到84.4%，并持续了2年以上。平均给药时间由93.3 min缩短至44.7 min。结论：系统的多学科方法减少了新生儿重症监护室从抗生素订购到给药时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.