Laser peripheral iridectomy use in the unoperated eyes of hospitalised patients with primary angle-closure glaucoma in a national multicentre study in China.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

BMC Ophthalmology Pub Date : 2026-05-07 DOI:10.1186/s12886-026-04873-y

Huiyan Mao, Kun Xiong, Yongzhen Yu, Qi'ao Zhang, Jinyuan Chen, Xue Yin, Dan Wang, Hong Sun, Xiaoli Xing, Guoping Duan, Zhiyang Jia, Jian Jiang, Zhengzheng Wu, Li Tang, Peng Lu, Danyan Liu, Yajuan Zheng, Lidong Zhuo, Sujie Fan, Xinying Zhang, Weiwei Liu, Yan Dai, Hong Chen, Huadong Xiang, Jingyi Lv, Yang Yang, Jianjun Ma, Jianfang Yang, Xueli Cao, Tingting Zhou, Wenyi Guo, Guoxing Li, Shaodan Zhang, Xin Sun, Mingguang He, Yuanbo Liang

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引用次数: 0

Abstract

Objective: To investigate the use of laser peripheral iridectomy (LPI) in the unoperated eyes of hospitalised patients with primary angle-closure glaucoma (PACG).

Methods: This was a national multi-centre retrospective study, and the sample was selected via multi-stage stratified random sampling from 26 hospitals. Data on LPI use were extracted from the electronic medical records (EMRs) of 5,404 PACG patients from 1 January 2011 to 31 December 2020. We used a generalised estimating equations (GEE) model to identify factors influencing LPI use.

Results: Among 3,525 unoperated eyes of hospitalised PACG patients, 35.3% of these eyes received LPI during hospitalisation, and the usage rate was 35.1% and 36.0% in provincial-level or above and in city-level hospitals, respectively. In multivariable models, an intraocular pressure (IOP) of > 21 mmHg (OR = 0.915; 95% CI [0.875, 0.956]), moderate visual impairment (OR = 0.898; 95% CI [0.849, 0.949]) and severe visual impairment or blindness (OR = 0.755; 95% CI [0.717, 0.794]) were associated with a lower LPI usage rate in unoperated eyes. By contrast, patients treated in the northern region had a higher LPI usage rate in unoperated eyes (OR = 1.343; 95% CI [1.295, 1.393]).

Conclusions: The usage rate of LPI in the unoperated eyes of PACG patients is relatively low in China, especially among patients in the southern region, with higher IOP and worse visual impairment.

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中国一项全国性多中心研究：原发性闭角型青光眼住院患者未手术眼激光周围虹膜切除术的应用

目的：探讨激光周围虹膜切除术（LPI）在原发性闭角型青光眼（PACG）住院患者未手术眼中的应用。方法：本研究为全国性多中心回顾性研究，采用多阶段分层随机抽样的方法从26家医院抽取样本。从2011年1月1日至2020年12月31日期间5404名PACG患者的电子病历（EMRs）中提取LPI使用数据。我们使用广义估计方程（GEE）模型来确定影响LPI使用的因素。结果：3525只PACG住院患者未手术眼中，35.3%的患者在住院期间接受了LPI治疗，省级以上医院LPI使用率为35.1%，市级医院LPI使用率为36.0%。在多变量模型中，眼压（IOP）为bb0 ~ 21 mmHg （OR = 0.915; 95% CI[0.875, 0.956]）、中度视力障碍（OR = 0.898; 95% CI[0.849, 0.949]）和重度视力障碍或失明（OR = 0.755; 95% CI[0.717, 0.794]）与未手术眼低LPI使用率相关。相比之下，北方地区患者未手术眼LPI使用率较高（OR = 1.343; 95% CI[1.295, 1.393]）。结论：中国PACG患者未手术眼LPI使用率较低，尤其是南方地区患者，IOP较高，视力损害较严重。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Ophthalmology OPHTHALMOLOGY-

CiteScore

3.40

自引率

5.00%

发文量

441

审稿时长

6-12 weeks

期刊介绍： BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.