Leah T Kienitz, Annette M McCoy, Mitchell A Robbins
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引用次数: 0
Abstract
Objective: Investigate effect of hyperbaric oxygen therapy (HBOT) on recovery of deep pain perception (DPP) in dogs after hemilaminectomy for thoracolumbar intervertebral disk disease (IVDD).
Methods: Records of client-owned dogs with absent DPP in pelvic limbs after hemilaminectomy for IVDD from January 2014 through December 2024 were retrospectively reviewed. Dogs undergoing hemilaminectomy were divided into groups: received HBOT (HB) and no HBOT (NHB). Modified Frankel scores were assigned between 0 (absent DPP in either pelvic limb) and 5 (spinal hyperesthesia) preoperatively, postoperatively, and at recheck examination. Outcomes were compared using the Pearson χ2 test. Regression analysis assessed if other factors were associated with improvement in Frankel score.
Results: 110 dogs with absent DPP had thoracolumbar hemilaminectomies, 45 in HB group and 65 in NHB group. Thirty-three of 45 HB cases (73.3%) and 39 of 65 NHB cases (60%) improved neurologically by recheck examination (P = .21). There were no differences in neurological improvement between groups at any time point (P = .32). Multivariable regression analysis revealed worse odds of improvement for thoracolumbar relative to lumbar lesions (OR, 0.01; 95% CI, 0.0008 to 0.49; P = .04). Improvement odds with thoracolumbar lesions were lower in NHB than HB group (contrast OR, 0.029; 95% CI, 0.027 to 0.031; P = .01). HBOT session amount was not associated with improvement (P = .65).
Conclusions: HBOT did not impact recovery of DPP after hemilaminectomy. Thoracolumbar lesions had lower odds of neurological improvement than lumbar lesions. Odds were improved with HBOT.
Clinical relevance: Findings may predict return to ambulation.
期刊介绍：
The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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