Prevalence of dementia among older persons in Northern Uganda, a cross-sectional study.

IF 0.9
Dan Langoya Oriba, Matovu Stephen Mwonge, Robert Mukisa, Martin N Kaddu-Mukasa, Felix Bongomin, Abdu K Musubire, Mark Kaddumukasa
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Abstract

Background: The burden and clinical correlates of dementia are unknown in Uganda. We therefore determined the prevalence and factors associated with dementia among older persons in Northern Uganda.

Methods: In a cross-sectional study, adults aged 60 years and above attending the medical outpatient clinic at a tertiary Hospital from March 2022 to April 2022 were enrolled. The prevalence of dementia was determined using the Intervention for Dementia in Elderly Africans (IDEA) and the Instrumental Activities of Daily Living (IADL) tool henceforth presented as IDEA-IADL. Factors of association were collected using a standardized questionnaire.

Results: A total of 271 eligible participants were enrolled into the study. Majority were age 60-69 years (153/271) and of male gender (165/271). The prevalence of dementia was 17.7% (48/271), severe dementia 7.4%, (20/271), moderate dementia 10.3%, (28/271). Factors independently associated with dementia were: participants aged between 80-89 years; (adjusted odds ratio (aOR): 9.7; 95% Confidence Interval (CI): 4.08-23.07, p< 0.001), family history of dementia (aOR: 3.4, 95CI: 1.62-7.04, p=0.001). history of depression (aOR: 2.7, 95CI: 1.40-5.02, p=0.003). Physical activity and cognitive exercise were associated protective factors with (aOR 0.1, 95CI: 0.03-0.24, p< 0.001) and (aOR 0.2, 95CI: 0.06-0.53, p<0.002) respectively.

Conclusion: There burden of dementia among older persons in Northern Uganda is significant. Enhanced screening and early identification of dementia is recommended in this setting.

乌干达北部老年人痴呆患病率的横断面研究。
背景:在乌干达,痴呆症的负担和临床相关因素尚不清楚。因此,我们确定了乌干达北部老年人中痴呆症的患病率和相关因素。方法:采用横断面研究方法,选取2022年3月至2022年4月在某三级医院内科门诊就诊的60岁及以上成年人。使用非洲老年痴呆症干预(IDEA)和日常生活工具性活动(IADL)工具确定痴呆的患病率,此后称为IDEA-IADL。使用标准化问卷收集相关因素。结果:共有271名符合条件的参与者被纳入研究。以60 ~ 69岁(153/271)和男性(165/271)居多。痴呆患病率17.7%(48/271),重度痴呆患病率7.4%(20/271),中度痴呆患病率10.3%(28/271)。与痴呆相关的独立因素有:参与者年龄在80-89岁之间;(调整后优势比:9.7;95%可信区间(CI): 4.08-23.07, p< 0.001)、痴呆家族史(aOR: 3.4, 95CI: 1.62-7.04, p=0.001)。抑郁史(aOR: 2.7, 95CI: 1.40 ~ 5.02, p=0.003)。体力活动和认知锻炼是相关的保护因素(aOR 0.1, 95CI: 0.03-0.24, p< 0.001)和(aOR 0.2, 95CI: 0.06-0.53, p)。结论:乌干达北部老年人痴呆负担显著。在这种情况下,建议加强对痴呆症的筛查和早期识别。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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