Gestational Age-Specific Prevalence of Retinopathy of Prematurity in Very Preterm Infants: An Exploratory Meta-Analysis.

IF 2.1 4区 医学 Q1 PEDIATRICS
Acta Paediatrica Pub Date : 2026-05-04 DOI:10.1111/apa.70570
Paige Scudder, Shiyu Zhang, Tora Sund Morken, Christiane E L Dammann, Olaf Dammann
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引用次数: 0

Abstract

Aim: To evaluate whether Retinopathy of Prematurity (ROP) research cohorts should be defined exclusively by gestational age (GA) thresholds rather than the current standard of combining GA with birth weight (BW).

Methods: Literature search of publications between 1971 and 2024, and data extraction using predefined search terms and inclusion criteria.

Results: ROP prevalence changes notably at around 28 weeks GA, decreasing appreciably at older gestational ages. Including BW alongside GA (as is done in some ROP screening guidelines) affects the variability of ROP prevalence data and may obscure the true population-level association between GA and ROP severity.

Conclusion: Clinical study populations for ROP research should be defined by GA thresholds only, without additional BW inclusion criteria.

极早产儿视网膜病变的胎龄特异性患病率:一项探索性meta分析。
目的:评价早产儿视网膜病变(ROP)研究队列是否应该完全由胎龄(GA)阈值来定义,而不是目前的胎龄与出生体重(BW)相结合的标准。方法:检索1971 ~ 2024年出版的文献,采用预设检索词和纳入标准进行数据提取。结果:ROP患病率在孕28周左右发生显著变化,在孕龄较大时明显下降。将体重和骨性关节炎(如某些ROP筛查指南中所做的那样)一起纳入会影响ROP患病率数据的可变性,并可能模糊骨性关节炎和ROP严重程度之间的真正人群水平关联。结论:ROP研究的临床研究人群应仅由GA阈值定义,而不需要额外的体重纳入标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Acta Paediatrica
Acta Paediatrica 医学-小儿科
CiteScore
6.50
自引率
5.30%
发文量
384
审稿时长
2-4 weeks
期刊介绍: Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries
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